Palmitoylethanolamide for Post-operative Pain Prevention — PEAforCPSP  

Chronic Post-operative Pain Clinical Trial

Official title: Perioperative Use of Palmitoylethanolamide for Prevention of Chronic Postsurgical Pain in Patients Undergoing Elective Surgery.

Status Not yet recruiting

Clinical Trial Summary

Postsurgical pain becomes chronic when it lasts more then two months after surgery. A neurogenic or neuropathic pathogenesis is hypothesized for this event that reaches high rates after urologic and gynecologic surgeries.

Palmitoylethanolamide (PEA) binds to mast cells and regulates pro-inflammatory factors release, without adverse events.

The investigators assume that perioperative administration of PEA can reduce chronic postsurgical pain incidence of patients undergoing to urologic and gynecologic elective surgery.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver), Primary Purpose: Prevention

Related Conditions & MeSH terms

• Chronic Post-operative Pain
• Pain, Postoperative

• NCT number: NCT01491191
• Study type: Interventional
• Source: University of Modena and Reggio Emilia
• Contact: Laura Rinaldi, MD
• Phone: 0390594224896
• Email: rinaldi.laura@unimore.it
• Status: Not yet recruiting
• Phase: N/A
• Start date: January 2012
• Completion date: July 2013