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Deep Brain Therapy With Low-intensity Ultrasound for Generalized Chronic Pain — DBT  

Chronic Pain Clinical Trial

Official title:
Deep Brain Therapy With Low-intensity Ultrasound for Generalized Chronic Pain: A Pilot Study of Target Engagement and Analgesic Effects

Clinical Trial Summary

This study will evaluate a new form of non-invasive deep brain therapy for individuals with generalized chronic pain. Low-intensity transcranial focused ultrasound stimulation will first be delivered using a range of stimulation parameters during psychophysical and physiological monitoring. A well-tolerated stimulation protocol will be selected for subsequent testing in a blinded randomized sham-controlled cross-over trial. The trial will evaluate brain target engagement using magnetic resonance imaging and CVAS and PROMIS numerical rating scales of pain.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05674903
Study type Interventional
Source University of Utah
Contact Jan Kubanek, PhD
Phone 801-213-1418
Email jan.kubanek@utah.edu
Status Recruiting
Phase Phase 1/Phase 2
Start date July 10, 2023
Completion date March 31, 2026
View Details
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