Clinical Trial Details
— Status: Completed
Administrative data
| NCT number |
NCT05485285 |
| Other study ID # |
?158 (23.05.2022) |
| Secondary ID |
|
| Status |
Completed |
| Phase |
|
| First received |
|
| Last updated |
|
| Start date |
February 24, 2022 |
| Est. completion date |
May 24, 2022 |
Study information
| Verified date |
July 2023 |
| Source |
Bogomolets National Medical University |
| Contact |
n/a |
| Is FDA regulated |
No |
| Health authority |
|
| Study type |
Observational [Patient Registry]
|
Clinical Trial Summary
Mine-explosive wounds in the general structure of combat sanitary losses reach 25%. They are
characterized by significant damage resulting in high intensity pain. In patients who
received mine-explosive injuries in the conditions of hostilities, such pain has its own
unique features. It is necessary to pay more attention to the problem of pain treatment in
patients of this category, because about 87.2% of cases have negative results of treatment -
it becomes chronic.
Description:
Over the last ten years, the amount of pathology caused by mine-explosive devices has
increased significantly. Mine-explosive wounds in the general structure of combat sanitary
losses reach 25%. They often have a combined character. Such an injury must be considered as
a multifactorial injury resulting from the combined impact on a person of a shock wave, gas
jets, flames, toxic products, fragments of the hull, secondary projectiles, which cause
severe injuries in the area of direct damage and the body as a whole. Mine-explosive injuries
are characterized by multiple, combined or combined injuries with a high degree of severity -
8-10%. Also, even in peacetime, terrorists often use powerful explosive devices. Here, the
mortality rate is 10-20% of the total number of injured, and 80-90% suffer from the
consequences - mine-explosive injuries. Compared to the wars of the past, the number of
seriously wounded with combined injuries has increased to 25-30%. This is primarily due to
the use of high-precision ammunition and mine-explosive ammunition. In general, multiple and
combined damage in local conflicts today is 25-62%. Lethality in case of mine-explosive
injury reaches 37-41.4%. The mortality rate among the wounded with mine-explosive injuries
who were admitted to the stage of qualified medical care was 17.4%, more than half of the
wounded died as a result of blood loss. In 63.7%, death occurs in the first 24 hours after
injury.The direct and most frequent causes are shock and blood loss (49.1%), destruction of
vital organs (28.4%). About 90% of all combat deaths occur before the wounded reaches the
first stage of treatment.
The peculiarities of pain in patients with mine-explosive wounds depending on the
localization of the wound at the stages of treatment need to be studied, because the
subjective feelings and emotional experiences experienced by patients during the wounding in
combat conditions through the prism of psychological disorders have their own
characteristics. Since in 87.2% of cases it is not possible to achieve a positive result of
treatment, the data of our study will play an important role in their treatment.
