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Clinical Trial Summary

This is an investigator-initiated study that is in the funding range for a grant from the NIH. This study is testing the possibility that non-invasive brain stimulation (ESSTim) would be superior to sham in the treatment of pain secondary to diabetic neuropathy.


Clinical Trial Description

The investigators hypothesize that Active ESStim will have a significantly improved and lasting effect compared to SHAM ESStim assessed in 40 DNP patients, 20 per group, given now for 5 consecutive days, 20 min/day, followed by 2 weeks of bi-weekly stimulation given 20 min/day (total stimulations n=11) and follow-ups at 2, 4, 6, & 8 weeks post-stim): 13 visits plus screening/ baseline (total 14 visits). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05469074
Study type Interventional
Source Case Western Reserve University
Contact Megan O'Neill O'Neill Miller
Phone 216-844-4720
Email megan.miller3@uhhospitals.org
Status Recruiting
Phase Phase 2
Start date February 25, 2022
Completion date August 1, 2024

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