fMRI in Deep Brain Stimulation

Status Recruiting

Clinical Trial Summary

With fMRI, we want to understand the mechanisms of brain neuromodulation in (dys)functional brain circuits, to obtain knowledge on involved brain networks in DBS.

Clinical Trial Description

Deep brain stimulation represents a neurosurgical treatment option for specific refractory neurological and psychiatric disorders. In these patients a specific brain target is stimulated through an electrode with the use of an implantable pulse generator (IPG). In a functional MRI (fMRI) experiment, the investigators intend to perform imaging during stimulation ON and compare brain activations with the stimulation OFF condition. In this way, they aim to elucidate the involved brain network in deep brain stimulation. Since the connectivity of deep brain structures is complex, different activation patterns are expected in-between subjects and conditions. If specific activation patterns during the stimulation ON condition can be related to treatment response, this is of important clinical value. These findings can lead to an optimization of the deep brain target or even to different useful targets for brain stimulation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03819738
Study type	Interventional
Source	Universitaire Ziekenhuizen Leuven
Contact	Tom Theys, PhD
Phone	016344241
Email	tom.theys@uzleuven.be
Status	Recruiting
Phase	N/A
Start date	March 24, 2017
Completion date	January 10, 2022

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