Imaging Non-brain Electromagnetic Activity in Healthy Adults Using MEG

Chronic Pain Clinical Trial

— BODMEG  

Official title:

Imaging Non-brain Electromagnetic Activity in Healthy Adults Using MEG

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03232723
• Other study ID #: 17-00684
• Status: Completed
• Phase: N/A
• Start date: August 1, 2017
• Est. completion date: September 7, 2017

Study information

• Verified date: June 2019
• Source: NYU Langone Health
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The primary purpose of this study is to determine the effectiveness of the Magnetoencephalography (MEG) instrument to record electrical activity from parts of the body other than the brain. This study will examine if electrical activity from parts of the body, other than the brain, can be imaged by the MEG instrument. Finding will contribute to studies of pain, since abnormal electrical activity in skeletal muscle is the basis of pain, which can be severe, yet there is no non-invasive way to image this abnormal activity. This is particularly relevant to deep muscle pain and back pain.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 10
• Est. completion date: September 7, 2017
• Est. primary completion date: September 7, 2017
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 90 Years

Eligibility

Inclusion Criteria:

• Healthy adults who are willing and able to provide informed consent.

Exclusion Criteria:

• Subjects with characteristics incompatible with MEG recordings as listed on the MEG Safety checklist (Appendix A),

• Involuntary, uncontrolled tremor,

• chronic pain.

• pregnant women (based on self-report).

Related Conditions & MeSH terms

• Chronic Pain

Intervention

Diagnostic Test:
• Whole-cortex MEG System (with optional EEG)
"Whole-Cortex MEG System" non- invasively measures the magnetoencephalographic (MEG) signals (and, optionally, electroencephalographic EEG signals) produced by electrically active tissue of the brain. These signals are recorded by a computerized data acquisition system, displayed, and may then be interpreted by trained physicians to help localize these active areas. The location may then be correlated with anatomical information of the brain. MEG is routinely used to identify the locations of visual, auditory, somatosensory, and motor cortex in the brain.

Locations

Country	Name	City	State
United States	New York University School of Medicine	New York	New York

Sponsors (1)

Lead Sponsor	Collaborator
NYU Langone Health

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Determination of optimal position to obtain safe and effective imaging of structures other than the brain.	Hand position 1 relaxed; Hand position 1 muscles active; Hand position 2 relaxed; Hand position 2 muscles active; Neck and Jaw, relaxed; Neck and Jaw, tensed; Upper torso relaxed; Area of interest 1 relaxed(areas are not specific for Runs 9-11. (Possible areas are groups of muscles in the back and limbs.); Area of interest 1 tensed(areas are not specific for Runs 9-11. (Possible areas are groups of muscles in the back and limbs.); Area of interest 2 relaxed(areas are not specific for Runs 9-11. (Possible areas are groups of muscles in the back and limbs.); Area of interest 2 tensed (areas are not specific for Runs 9-11. (Possible areas are groups of muscles in the back and limbs.)	2 Weeks
Primary	Evoked activity to obtain safe and effective imaging of structures other than the brain	Hand position 1 relaxed; Hand position 1 muscles active; Hand position 2 relaxed; Hand position 2 muscles active; Neck and Jaw, relaxed; Neck and Jaw, tensed; Upper torso relaxed; Area of interest 1 relaxed(areas are not specific for Runs 9-11. (Possible areas are groups of muscles in the back and limbs.); Area of interest 1 tensed(areas are not specific for Runs 9-11. (Possible areas are groups of muscles in the back and limbs.); Area of interest 2 relaxed(areas are not specific for Runs 9-11. (Possible areas are groups of muscles in the back and limbs.); Area of interest 2 tensed (areas are not specific for Runs 9-11. (Possible areas are groups of muscles in the back and limbs.)	2 Weeks
Secondary	Dominant frequency of non-brain electrical activity in healthy adults.	Hand position 1 relaxed; Hand position 1 muscles active; Hand position 2 relaxed; Hand position 2 muscles active; Neck and Jaw, relaxed; Neck and Jaw, tensed; Upper torso relaxed; Area of interest 1 relaxed(areas are not specific for Runs 9-11. (Possible areas are groups of muscles in the back and limbs.); Area of interest 1 tensed(areas are not specific for Runs 9-11. (Possible areas are groups of muscles in the back and limbs.); Area of interest 2 relaxed(areas are not specific for Runs 9-11. (Possible areas are groups of muscles in the back and limbs.); Area of interest 2 tensed (areas are not specific for Runs 9-11. (Possible areas are groups of muscles in the back and limbs.)	2 Weeks
Secondary	Location of non-brain of activity in healthy adults.	Hand position 1 relaxed; Hand position 1 muscles active; Hand position 2 relaxed; Hand position 2 muscles active; Neck and Jaw, relaxed; Neck and Jaw, tensed; Upper torso relaxed; Area of interest 1 relaxed(areas are not specific for Runs 9-11. (Possible areas are groups of muscles in the back and limbs.); Area of interest 1 tensed(areas are not specific for Runs 9-11. (Possible areas are groups of muscles in the back and limbs.); Area of interest 2 relaxed(areas are not specific for Runs 9-11. (Possible areas are groups of muscles in the back and limbs.); Area of interest 2 tensed (areas are not specific for Runs 9-11. (Possible areas are groups of muscles in the back and limbs.)	2 Weeks