The Effects of TAP Block on Postsurgical Pain After Minimally Invasive Partial Nephrectomy:

Chronic Pain Clinical Trial

Official title:

The Effects of Ultrasound-guided Transversus Abdominis Plane Block on Acute and Chronic Postsurgical Pain After Robotic Partial Nephrectomy. A Prospective, Randomized, Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02460640
• Other study ID #: Tap Block
• Status: Completed
• Phase: N/A
• First received: May 19, 2015
• Last updated: January 31, 2018
• Start date: May 2015
• Est. completion date: August 2017

Study information

• Verified date: January 2018
• Source: Regina Elena Cancer Institute
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Single-center study in order to assess whether the tap block can make extremely beneficial in terms of reducing the acute and chronic pain as well as for use of opioids and side effects related to it in patients undergoing surgery to minimally invasive partial nephrectomy.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 96
• Est. completion date: August 2017
• Est. primary completion date: August 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• asa score I,II,II

• patients scheduled for robot assisted partial nephrectomy

Exclusion Criteria:

• previous abdominal surgery

• inability to provide informed consent

• allergy to the anesthetic drugs

Related Conditions & MeSH terms

• Acute Pain
• Chronic Pain

Intervention

Procedure:
• Tap block
intravenous patient-controlled analgesia with morphine and tap block with subcostal and posterior approach with ropivacaine 0,5% 15ml+15ml
• intravenous Patient controlled analgesia
intravenous patient-controlled analgesia with morphine

Drug:
• Morphine

• Ropivacaine

Locations

Country	Name	City	State
Italy	Regina Elena CI	Rome

Sponsors (1)

Lead Sponsor	Collaborator
Regina Elena Cancer Institute

Country where clinical trial is conducted

Italy, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Morphine consuption 24 hr after surgery	Cumulative morphine consuption (mg) 24 hr starting from the time of extubation.	24 hours
Primary	Acute pain after surgery measured with Numerical Rating Scale	patients were assessed for pain, according to Numerical Rating Scale (NRS; 0: no pain to 10: worst pain imaginable)	24 hours