Sublingual Buprenorphine for Chronic Pain

Status Not yet recruiting

Clinical Trial Summary

The purpose of this study is to develop and pilot test clinical guidelines for the use of buprenorphine for the treatment chronic pain among patients with substance abuse histories. Buprenorphine, an opioid medication, holds promise as a treatment of chronic pain because, compared to most other opioid analgesics, it has a high safety profile, a low level of physical dependence, and mild withdrawal symptoms on cessation. Moreover there are promising reports from Europe of its use as a skin patch to treat chronic pain as well as clinical reports in the U.S. that it may be effective when used sublingually (placed under the tongue). This study will test the sublingual formulation.

Clinical Trial Description

n/a

Study Design

Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Chronic Pain

Clinical Trial Details

NCT number	NCT00612287
Study type	Interventional
Source	National Institute on Drug Abuse (NIDA)
Contact	Russell K Portenoy, MD
Phone	212-844-1505
Email	Rportenoy@bethisrael.org
Status	Not yet recruiting
Phase	Phase 2
Start date	April 2009
Completion date	August 2009

View Details

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