Chronic Pain Syndrome Clinical Trial
Official title:
The Effect of an Additional Bolus Application in Patients With Intrathecal Opiate Administration - a Pilot Study
An additional, intermittent bolus application in patients with intrathecal opiate
administration for chronic pain syndrome may have a positive effect on the effectiveness of
the treatment. Thus, the effect of an additional, intermittent bolus application in patients
with intrathecal opiate administration was therefore investigated.
Patients already equipped with an intrathecal opiate pump were enrolled into the study. Each
patient was submitted to two treatment periods in randomly chosen order (cross-over design):
1. standard treatment (continuous opiate administration) and 2. continuous opiate
administration with intermittent opiate bolus application. Both treatment periods lasted 14
days. Patients were asked to record pain intensity, side effects and satisfaction with the
treatment.
The following hypotheses were tested:
- The application of additional opiate boli results in significantly lower pain
intensity.
- The application of additional opiate boli does not result in a higher rate of adverse
Events.
n/a
Observational Model: Case-Crossover, Time Perspective: Prospective
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT01417923 -
The Immune and Clinical Impacts of Vitamin D in Patients With Chronic Musculo-skeletal Pain
|
Phase 4 | |
| Completed |
NCT03472521 -
Prevention of Persistent Opioid Use in Mothers
|
Phase 4 | |
| Not yet recruiting |
NCT03249025 -
Lidocaine-Ketamine for Management of Chronic Pain
|
N/A | |
| Enrolling by invitation |
NCT06359561 -
Assessment of Effectiveness and Stimulation Coverage of Closed-loop Spinal Cord Stimulation (CL-SCS) Therapy in Patients With Cervical Lead Placement
|
||
| Recruiting |
NCT05877274 -
Sodium Channel Mutations in Patient With the Anterior Cutaneous Nerve Entrapment Syndrome (ACNES)
|
||
| Completed |
NCT03317782 -
NoL Index Variations Before and After a Stellate Ganglion Block
|
||
| Completed |
NCT04199858 -
Electrophysiological Correlates of Nocebo Effects on Pain
|
N/A | |
| Recruiting |
NCT05491499 -
Assessing the Impact of Exercise Based Intensive Interdisciplinary Pain Treatment (IIPT) on Endogenous Pain Modulation in Youth With Chronic Pain Syndromes
|
||
| Active, not recruiting |
NCT05090683 -
Evaluation of a Mind-body Based Application for the Treatment of Chronic/Persistent Pain.
|
N/A | |
| Completed |
NCT04197154 -
Pain-related Fear as a Facilitator of Nocebo Hyperalgesia
|
N/A | |
| Completed |
NCT04209764 -
Prevalence of Pain in the Departments of Surgery and Oncoematology of a Children's Hospital
|
||
| Recruiting |
NCT06072573 -
Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Diabetic Polyneuropathy
|
Phase 3 | |
| Recruiting |
NCT06071988 -
Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Traumatic or Post-operative Peripheral Neuropathy
|
Phase 3 | |
| Recruiting |
NCT06071962 -
Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Back Pain
|
Phase 3 | |
| Recruiting |
NCT06071975 -
Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Diabetic Polyneuropathy
|
Phase 3 | |
| Recruiting |
NCT06072001 -
Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis
|
Phase 3 | |
| Recruiting |
NCT06072560 -
Efficacy and Tolerability of AP707 in Patients With Chronic Back Pain
|
Phase 3 | |
| Recruiting |
NCT06071936 -
Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Traumatic or Post-operative Peripheral Neuropathy
|
Phase 3 | |
| Recruiting |
NCT06071949 -
Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis
|
Phase 3 | |
| Completed |
NCT03460717 -
Thermal Micro-cautery for Painful Knee Osteoarthritis
|
N/A |