Chronic Lymphoid Leukaemia Clinical Trial
— OFICE| NCT number | NCT03294980 |
| Other study ID # | OFICE |
| Secondary ID | |
| Status | Recruiting |
| Phase | |
| First received | |
| Last updated | |
| Start date | November 2015 |
| Est. completion date | November 2025 |
Brief Summary: The purpose of the OFICE registry is to characterize and describe the CLL patients' population from the Finistere area and evaluates the association between different patient characteristics, prognosis and treatment patterns. Detailed Description: OFICE is a single center, prospective, observational registry of CLL patients designed to provide a general description of the CLL patients' population from the Finistere area, France. The registry will also provide information on the association of cytogenetic and immunophenotypic characteristics with disease progression, as well as treatment patterns and healthcare resource utilization. These data will be accessible and beneficial for researchers and physicians and will help guide clinical practice and future clinical or fundamental studies.
| Status | Recruiting |
| Enrollment | 3000 |
| Est. completion date | November 2025 |
| Est. primary completion date | November 2025 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 18 Years and older |
| Eligibility | Inclusion Criteria: - Age of at least 18 years - Clinical diagnosis of CLL/SLL that meets published diagnostic criteria (Hallek 2008) - Willing and able to provide informed consent - Willing and able to provide blood sample at time of enrollment Exclusion Criteria: - Diagnosis of other B-cell malignancies |
| Country | Name | City | State |
|---|---|---|---|
| France | CHRU de Brest | Brest |
| Lead Sponsor | Collaborator |
|---|---|
| University Hospital, Brest |
France,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Prevalence | Clinical data | Year 0 (Y) | |
| Secondary | Incidence | Clinical and biological data | Year 0 | |
| Secondary | Description of baseline clinical-biological | Clinical data, complete blood count, Matutes score and parameters, cytogenetic, IgVH mutations, CD38 (%), medical treatment will be collected | Year 0, Year 1, Year 2, Year 3 |