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Chronic Lymphocytic Leukemia clinical trials

View clinical trials related to Chronic Lymphocytic Leukemia.

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NCT ID: NCT05999877 Active, not recruiting - Clinical trials for Chronic Lymphocytic Leukemia

PICAROS - Acalabrutinib RWE on 1L CLL in Spain

PICAROS
Start date: July 11, 2023
Phase:
Study type: Observational

This is a multicenter non-interventional study (NIS) on patients with CLL who have been treated with acalabrutinib for the first time within the year before the first site initiation visit in Spain

NCT ID: NCT05972577 Active, not recruiting - Clinical trials for Acute Myeloid Leukemia

Geriatric Optimization Plan to Improve Survival in Older Adult Allogeneic Hematopoietic Cell Transplant Candidates, OTIS Study

Start date: June 2, 2021
Phase: N/A
Study type: Interventional

This clinical trial tests whether a geriatric optimization plan (GO!) works to improve survival in patients over 60 with a hematologic malignancy or bone marrow failure syndrome eligible for allogeneic hematopoietic cell transplant. GO! focuses on creating a tailored and specific plan for each patient to make changes in their daily lives. These may include changes to their diet, sleep, activity, medicines, or even referrals to other providers depending on the patient's needs. Studying survival and quality of life in patients over 60 receiving an allogeneic hematopoietic cell transplant may help identify the effects of treatment.

NCT ID: NCT05971251 Recruiting - Clinical trials for Chronic Lymphocytic Leukemia

Addition of Loncastuximab Tesirine to Acalbrutinib , Chronic Lymphocytic Leukemia

Start date: December 18, 2023
Phase: Phase 1
Study type: Interventional

Study is a phase I study to determine the maximum tolerated dose of adding Loncastuximab Tesirine to Aclabrutinib in the treatment of chronic lymphocytic leukemia.

NCT ID: NCT05959694 Recruiting - Clinical trials for Chronic Lymphocytic Leukemia

A Clinical Trial on the Safety and Efficacy of TQB3909 Tablets in Patients With Recurrent or Refractory Chronic Lymphocytic Leukemia (CLL) /Small Lymphocytic Lymphoma (SLL) .

Start date: October 11, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

This is a phase Ib/II clinical trial to evaluate the safety and efficacy of TQB3909 tablets in patients with recurrent or refractory CLL/SLL.

NCT ID: NCT05950997 Recruiting - Clinical trials for Chronic Lymphocytic Leukemia

A Single Arm Study of Acalabrutinib Conbimed With Obinutuzumab in Chinese Patients With Previously Untreated CLL

Start date: January 31, 2024
Phase: N/A
Study type: Interventional

This is a single-arm, prospective study to assess the efficacy and safety of acalabrutinib combined with obinutuzumab in subjects with previously untreated chronic lymphocytic leukemia.

NCT ID: NCT05943496 Recruiting - Clinical trials for Chronic Lymphocytic Leukemia

Tafasitamab, Acalabrutinib, and Obinutuzumab for the Treatment of Previously Untreated Chronic Lymphocytic Leukemia

Start date: October 2, 2023
Phase: Phase 1
Study type: Interventional

This phase Ib trial tests the safety and effectiveness of tafasitamab, acalabrutinib, and obinutuzumab in treating patients with previously untreated chronic lymphocytic leukemia (CLL). CLL is a type of cancer that develops from a specific white blood cell called B cells or B lymphocytes. Tafasitamab and obinutuzumab are monoclonal antibodies that may interfere with the ability of cancer cells to grow and spread. Acalabrutinib is in a class of medications called kinase inhibitors. It blocks a protein called BTK, which is present on B-cell cancers such as CLL at abnormal levels. This may help keep cancer cells from growing and spreading. Giving tafasitamab, acalabrutinib, and obinutuzumab may kill more cancer cells in patients with previously untreated CLL.

NCT ID: NCT05928156 Completed - Multiple Myeloma Clinical Trials

Multiple Myeloma/Chronic Lymphocytic Leukemia Coach RCT

Start date: December 17, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to test the effectiveness of evidence-informed mobile apps, Myeloma Coach and CLL Coach. These apps have been developed to help manage the physical and emotional symptoms experienced by multiple myeloma and chronic lymphocytic leukemia survivors. This study hopes to determine if a mobile app is a useful tool to help people manage commonly reported symptoms related to Multiple Myeloma (MM) and chronic lymphocytic leukemia (CLL).

NCT ID: NCT05899543 Not yet recruiting - Clinical trials for Chronic Lymphocytic Leukemia

Determining Clinical Study Experiences of Chronic Lymphocytic Leukemia Patients

Start date: July 2024
Phase:
Study type: Observational

This research study aims to address the limited understanding of the challenges faced by specific demographic groups of chronic lymphocytic leukemia patients in their participation in clinical trials. This trial will scrutinize the experiences of patients diagnosed with chronic lymphocytic leukemia as they take part in a separate medical intervention clinical trial. The focus will be on tracking the rates of completion and withdrawal among these individuals. It will also try to analyze data from the perspective of different demographic groups to check for recurring trends which might yield insights for the sake of future chronic lymphocytic leukemia patients.

NCT ID: NCT05879133 Recruiting - Clinical trials for Chronic Lymphocytic Leukemia

HEALTH4CLL2: A Randomized Waitlist Control Trial of Behavioral Interventions in Patients With Chronic Lymphocytic Leukemia

Start date: May 17, 2023
Phase: N/A
Study type: Interventional

To learn if exercise and weight management can help to improve feelings of fatigue in CLL survivors.

NCT ID: NCT05878184 Recruiting - Clinical trials for Chronic Lymphocytic Leukemia

Study Evaluating SC291 in Subjects With r/r B-cell Malignancies (ARDENT)

Start date: May 2, 2023
Phase: Phase 1
Study type: Interventional

SC291-101 is a Phase 1 study to evaluate SC291 safety and tolerability, anti-tumor activity, cellular kinetics, immunogenicity, and exploratory biomarkers.