Chronic Lymphocytic Leukemia (CLL) Clinical Trial
Patients with chronic lymphocytic leukemia (CLL)have had very poor humoral responses to
pneumococcal polysaccharide vaccine (PPV). The vaccine in which pneumococcal polysaccharide
antigens are conjugated to protein (PCV) have been immunogenic in CLL patients in our
previous studies.
The purpose of this study is to evaluate the duration of these vaccine-induced antibodies
and the function of memory cells by giving a one dose of PPV-vaccine after several years of
PCV-vaccination.
n/a
Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Prevention
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