Chronic Knee Pain Clinical Trial
Official title:
A Retrospective Single-center Cohort Study on Patients With Chronic Knee Pain Treated With Conventional Radiofrequency of the Genicular Nerves
Management of chronic knee pain remains a challenge to the treating physician. A radiofrequency treatment of the genicular nerves is a not yet established but promising technique. This procedure is minimal invasive and has few adverse events. For these reasons it can be advantageous and fulfilling the unmet needs of these chronic knee pain patients warranting further research of its efficacy. To investigate this efficacy, all patients treated with radiofrequency ablation in the multidisciplinary chronic pain center between 1 September 2017 and 31 December 2019 with exclusion of patients with chronic widespread pain, will be retrospectively analyzed in a single-center cohort.
This project has as primary objective the evaluation of treatment success of a conventional radiofrequency treatment of the genicular nerves in patients diagnosed with chronic knee pain due to osteoarthritis of the knee or persistent post-surgical pain (PPSP) at six weeks post treatment. Secondary objectives are evaluation of treatment effect at a third time point at the end of the inclusion period, subgroup analysis of treatment success based on indication to treatment, evaluation of subjective functional improvement and change in analgesics, estimation of the duration of effect of the treatment and adverse events. This study includes all patients treated with radiofrequency ablation in the multidisciplinary chronic pain center in Ziekenhuis Oost-Limburg, Campus Sint-Barbara between 1 September 2017 and 31 December 2019 with exclusion of patients with chronic widespread pain. The main study outcome is the proportion of patients with a global perceived effect of at least 50% at 6 weeks post intervention. Secondary outcomes include reduction in pain intensity, measured by Numeric Rating Scale (NRS) at six weeks and at a third time point, global perceived effect at a third time point, subjective change in physical functioning, duration effect of the treatment, use of strong opioids, and adverse events. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT05920382 -
Radiofrequency Ablation for the Treatment of Post-knee Arthroplasty Chronic Pain.
|
N/A | |
Active, not recruiting |
NCT06340035 -
Percutaneous Peripheral Nerve Stimulation of Gluteus Nerves to Improve Hip Strength and Power
|
N/A | |
Recruiting |
NCT05473663 -
Radiofrequency Ablation After Total Knee Arthroplasty
|
N/A | |
Withdrawn |
NCT05335486 -
Investigating RELEARN Neurofeedback as Treatment for Chronic Musculoskeletal Pain
|
Phase 2/Phase 3 | |
Completed |
NCT05031104 -
Low-energy Laser Applications in Patients With Juvenile Idiopathic Arthritis
|
N/A | |
Not yet recruiting |
NCT06000709 -
Comparison Between Ultrasound-Guided Genicular Nerve Phenol Neurolysis and Intra-articular Steroid Injections
|
Phase 4 | |
Completed |
NCT05003323 -
Brain Biomarker of Endogenous Analgesia in Patients With Chronic Knee Pain
|
||
Recruiting |
NCT04580732 -
Clinical Trial of the MiniStim PNS for Knee Pain- "FLEX" Study
|
N/A | |
Terminated |
NCT04601168 -
Assessment of the Safety and Performance of a Compression Knee Support in the Prevention of Injuries During Sports Practice
|
||
Completed |
NCT01977872 -
JointADventure: A Worksite Activity-Diet Intervention for Chronic Knee Pain
|
N/A | |
Recruiting |
NCT05407610 -
Comparison of Conventional and Cooled Radiofrequency of the Genicular Nerves in Patients With Chronic Knee Pain
|
N/A | |
Recruiting |
NCT05816798 -
Photobiomodulation in Chronic Knee Pain in Patients Who Are in PreRehabilitation for Bariatric Surgery
|
Phase 2/Phase 3 | |
Terminated |
NCT04275128 -
Cooled Versus Conventional Genicular Radiofrequency Ablation for Chronic Knee Pain
|
||
Completed |
NCT05315934 -
Comparing the Effects of Upper and Lower Body Aerobic Exercise on Pain in Individuals With Chronic Knee Pain
|
N/A | |
Completed |
NCT02931435 -
Radiofrequency For Chronic Knee Pain Post-Arthroplasty
|
N/A | |
Completed |
NCT05137080 -
Dexamethasone and Functional Outcome After TKA
|
Phase 4 | |
Not yet recruiting |
NCT06133738 -
Effects of iCBT and Exercise for Chronic Knee Patients
|
N/A | |
Recruiting |
NCT05251142 -
Plyometric Training in Volleyball Players With Chronic Knee Pain
|
N/A | |
Recruiting |
NCT06004882 -
Peripheral Nerve Stimulation of Genicular Nerves Versus Conventional Therapy With Intra-articular Steroid Injection for Chronic Knee Pain: A Prospective, Randomized Pilot Study
|
N/A |