Chronic Hepatitis C Virus Infection Clinical Trial
Official title:
Efficacy and Safety of Sofosbuvir Plus Daclatasvir With or Without Ribavirin: Large Real-life Results of Patients With Chronic Hepatitis C Genotype 4
This study aims to evaluate the efficacy and safety of DCV plus sofosbuvir (SOF) with or without ribavirin (RBV) for treatment of Egyptian participants infected with HCV GT4.
Egyptian participants infected with HCV GT4 were classified into two groups: group 1 (easy to
treat) was treated with a dual therapy of SOF/DCV daily for 12 weeks and group 2 (difficult
to treat) was treated with a triple therapy of SOF/DCV/RBV daily for 12 weeks.
SOF dose was 400 mg/day given orally DCV was given in a dose of 60 mg/day, orally. RBV was
given as oral tablets in the morning and in the evening based on patient's weight and
tolerability (starting dose 600 mg/day to reach 1200 mg/day.
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