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Chronic Hepatitis C clinical trials

View clinical trials related to Chronic Hepatitis C.

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NCT ID: NCT00601770 Completed - Chronic Hepatitis C Clinical Trials

Virological Response Study of the HCV Vaccine IC41

Start date: February 2006
Phase: Phase 2
Study type: Interventional

The objective is to investigate the virological (HCV-RNA) responses following biweekly immunization with IC41. Treatment phase 14 weeks, total study duration including follow-up period 38 weeks.

NCT ID: NCT00596960 Completed - Chronic Hepatitis C Clinical Trials

Study of the Effects of Motivational Enhancement Therapy on Alcohol Use in Chronic Hepatitis C Patients

Start date: November 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether motivational enhancement therapy (MET) reduces alcohol use in a population of HCV-infected veterans who are currently drinking alcohol and have alcohol disorders. We hypothesize that veterans with HCV, an alcohol use disorder and continued excessive alcohol use who receive MET will have a greater reduction in the number of standard alcohol drinks per week and a greater percentage of days abstinent than veterans who receive health education control intervention.

NCT ID: NCT00591214 Completed - Chronic Hepatitis C Clinical Trials

Safety and PK Study of MP-424 to Treat Chronic Hepatitis C

Start date: December 2007
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the safety, pharmacokinetics and HCV(Hepatitis C virus) RNA (Ribonucleic Acid) kinetics after administration of MP-424 to patients with chronic hepatitis C.

NCT ID: NCT00575224 Completed - Chronic Hepatitis C Clinical Trials

Pegasys and Copegus for Asian Patients With Treatment-naive Hepatitis C Genotypes 6, 7, 8, 9

Start date: October 2004
Phase: Phase 4
Study type: Interventional

The purpose of this research study is to test the safety, tolerability, and effectiveness of the drugs Pegasys and Copegus when used for hepatitis C genotypes 6, 7, 8, and 9. Patients are randomly assigned (by chance) to either Treatment Group A (Pegasys and Copegus for 24 weeks) or Treatment Group B (Pegasys and Copegus for 48 weeks).

NCT ID: NCT00570336 Completed - Clinical trials for Chronic Hepatitis C Virus Infection

Study of CTS-1027 in Hepatitis C Patients

Start date: December 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if CTS-1027 can lower elevated liver enzymes in patients with chronic HCV infection.

NCT ID: NCT00559247 Completed - Chronic Hepatitis C Clinical Trials

A Single Ascending Dose Study of BMS-650032 in HCV Infected Subjects

Start date: January 2008
Phase: Phase 1/Phase 2
Study type: Interventional

The primary purpose of this study is to evaluate the safety profile and tolerability of single oral doses of BMS-650032 in subjects with chronic hepatitis C infection

NCT ID: NCT00556504 Completed - Chronic Hepatitis C Clinical Trials

The Effects of Adding TCM-700C on the Standard Combination Treatment for Patients With Genotype 1 Hepatitis C Infection

TCM-700C
Start date: July 2007
Phase: Phase 2
Study type: Interventional

The primary objective of this study is to evaluate the effectiveness of TCM-700C as an add-on treatment to the combination drug therapy (Peginterferon α-2b plus Ribavirin) for patients with genotype 1 chronic hepatitis C infections. This will be demonstrated by a higher sustained virologic response rate, defined as the absence of detectable HCV RNA 24 weeks after the termination of combinational drug treatment, compared with the placebo add-on.

NCT ID: NCT00546715 Completed - Chronic Hepatitis C Clinical Trials

A Single Ascending Dose Study of Daclatasvir (BMS-790052) in Hepatitis C Virus Infected Subjects

Start date: November 2007
Phase: Phase 1/Phase 2
Study type: Interventional

The primary purpose of this study is to evaluate the safety profile and tolerability of single oral doses of daclatasvir in subjects with chronic hepatitis C infection

NCT ID: NCT00546442 Completed - Chronic Hepatitis C Clinical Trials

Treatment Insulin Resistence in HCV G-1 Patient

TRIC-1
Start date: May 2006
Phase: Phase 4
Study type: Interventional

To evaluate the effect of treatment of insulin resistance in the response of chronic hepatitis C treatment, mesure as HCV-RNA negative at week 72. 4.3.2 Objetivos secundarios To evaluate the efficacy and safety of treatment with metformine to erradicate the insulin resistance of patients with chornic hepatitis C genotype 1 measure as HOMA-IR < 2.

NCT ID: NCT00540345 Completed - Chronic Hepatitis C Clinical Trials

Four Arms, Multicenter Study of Tailored Regimens With Peginterferon Plus Ribavirin for Genotype 2 Chronic Hepatitis C

Start date: October 2006
Phase: Phase 4
Study type: Interventional

The purposes of this study are: 1. To evaluate the efficacy and safety of low-dose versus standard-dose of ribavirin in combination with peginterferon alfa-2a given for 16 weeks in hepatitis C virus (HCV) genotype 2 infected, treatment-naïve chronic hepatitis C patients after achieving a rapid virologic response (RVR,defined as seronegativity of HCV RNA at week 4 of treatment). 2. To evaluate the efficacy and safety of 24-week versus 48-week regimen of peginterferon alfa-2a plus standard-dose of ribavirin in HCV genotype 2 infected, treatment-naïve chronic hepatitis C patients who have no RVR.