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Clinical Trial Summary

This is a multicenter, randomized, open, blank controlled trial ,in order to evaluate the effectiveness and safety of Amibufenamide(TMF) in the treatment of chronic hepatitis B virus infection patients with normal ALT .


Clinical Trial Description

Although the indications for antiviral therapy for patients with chronic hepatitis B have been gradually expanded in different guidelines, antiviral treatment efficacy remains unclear among patients with alanine aminotransferase (ALT) < 1 upper limits of normal (ULN). This study aimed to evaluate the the effectiveness and safety of TMF for these patients. Tenofovir amibufenamide (TMF; codename: HS-10234), another formulation of tenofovir, shared the same ProTide technology as tenofovir alafenamide, which can provide more efficient intracellular delivery than TDF. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05797714
Study type Interventional
Source Ruijin Hospital
Contact
Status Active, not recruiting
Phase N/A
Start date June 8, 2022
Completion date April 15, 2026

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