Precision Nutrition and Food Safety for Dietary Prevention of Chronic Disease Study

Chronic Diseases Clinical Trial

— PNFS  

Official title:

Precision Nutrition and Food Safety for Dietary Prevention of Chronic Disease (PNFS) Study

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT05247632
• Other study ID #: Cohort-PNFS
• Status: Active, not recruiting
• Start date: May 1, 2018
• Est. completion date: July 1, 2028

Study information

• Verified date: March 2023
• Source: Zhejiang University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The associations between food nutrition and safety factors with the risk of chronic diseases are still unclear. This study is conducted in Jinhua, a city with a high prevalence of chronic diseases in China, to assess relations between food nutrition and safety factors and chronic diseases.

Description:

Investigations of associations of food nutrition and safety factors with the risk of chronic diseases are limited and studies in China are still lacking. The investigators aim to collect basic characteristics of participants at baseline, including sex, age, smoking, exercise, marriage, education level, dietary factors, and so on, to assess the association of food nutrition and safety factors including various food items, dietary fatty acids, and internal biomarkers of food contaminants such as acrylamide and 3-MCPD with various chronic diseases in a Chinese middle-aged and elderly population. We will use multi-omics technology to investigate the causal mechanisms. Results from this study will be valuable for chronic diseases prevention in China.

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 2290
• Est. completion date: July 1, 2028
• Est. primary completion date: May 1, 2024
• Gender: All
• Age group: 45 Years to 75 Years

Eligibility

Inclusion Criteria:

• Subject aged =45 and =74 years old
• Subject has complete data on diet and follow-up time Exclusion Criteria: had the major illness that had made personal life disabled

Related Conditions & MeSH terms

• Chronic Disease
• Chronic Diseases

Locations

Country	Name	City	State
China	Lanxi Hospital of Traditional Chinese Medicine	Jinhua
China	Lanxi Red Cross Hospital	Lanxi	Zhejiang

Sponsors (3)

Lead Sponsor	Collaborator
Zhejiang University	Lanxi Hospital of Traditional Chinese Medicine, Lanxi Red Cross Hospital

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Numbers of participants with fatty liver disease	Fatty liver disease	From entry into the study baseline:2018 until 2023
Primary	Numbers of participants with metabolic syndrome	metabolic syndrome	From entry into the study baseline:2018 until 2023
Primary	Numbers of participants with obesity	Obesity	From entry into the study baseline:2018 until 2023
Primary	Numbers of participants with diabetes	Diabetes	From entry into the study baseline:2018 until 2023
Secondary	Numbers of participants died	All-cause and cause-specific mortality	From entry into the study baseline:2018 until 2023
Secondary	Numbers of participants with cardiovascular diseases	Cardiovascular diseases	From entry into the study baseline:2018 until 2023