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Changes in Bile Acid Homeostasis and Stool Habits After Cholecystectomy — BACH  

Cholelithiasis Clinical Trial

Official title:
Changes in Bile Acid Homeostasis and Stool Habits After Cholecystectomy

Clinical Trial Summary

Investigate serial plasma samples of fibroblast growth factor 19 (FGF19) after oral stimulation with chenodeoxycholic acid in the same subjects before and after elective cholecystectomy

Clinical Trial Description

Lack of FGF19 and elevated 7-alpha-hydroxy-colestenone (C4) is associated with the bile acid diarrhoea (BAD), a disease with increasing estimated of prevalence. BAD is occasionally triggered by cholecystectomy and FGF19 and C4 is known to be affected by cholecystectomy. The investigators are exploring if FGF19 after oral stimulation can be developed to a universal test for BAD, and need to know how the proposed test is affected by cholecystectomy. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03168555
Study type Interventional
Source Zealand University Hospital
Contact
Status Completed
Phase Phase 4
Start date June 22, 2017
Completion date May 15, 2019
View Details
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