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Clinical Trial Summary

OBJECTIVES:

I. Evaluate the effects of cladribine (2-chlorodeoxyadenosine; 2-CdA) on biochemical, radiologic, and histologic parameters in patients with early stage primary sclerosing cholangitis.


Clinical Trial Description

PROTOCOL OUTLINE:

Patients are treated with subcutaneous injections of cladribine (2-chlorodeoxyadenosine; 2-CdA) for 5 consecutive days every month for 3 months. ;


Study Design

Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT00004762
Study type Interventional
Source Office of Rare Diseases (ORD)
Contact
Status Completed
Phase Phase 2
Start date December 1994

See also
  Status Clinical Trial Phase
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Terminated NCT03359174 - An Efficacy Trial of Low Dose All-trans Retinoic Acid in Patients With Primary Sclerosing Cholangitis Phase 2
Completed NCT00004842 - Pilot Study of Budesonide for Patients With Primary Sclerosing Cholangitis Phase 1
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Recruiting NCT04181138 - Primary Sclerosing Cholangitis in Children
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