Children Clinical Trial
Official title:
Acute Lung Injury in Children: Epidemiology and Natural History: The Pediatric ALIEN Study
Acute lung injury in children is a syndrome of rapid onset of acute respiratory failure and require admission into intensive care units (ICU) for advanced life support. There are almost no information on epidemiology of acute lung injury. Published studies do not have information for an entire year and none of them have evaluated the degree of oxygenation failure under standard ventilator settings. The investigators will perform a 1-year prospective audit of all patients admitted with acute lung injury in a network of pediatric ICUs in Spain.
We will evaluate oxygenation under standard ventilator settings (FiO2 0.5 and 1 on PEEP 5 or
10 cmH2O) in pediatric acute respiratory distress syndrome.
Outcome measures will include: overall ICU mortality, number of patients meeting ARDS
criteria at 24 hours, and stratification of patients depending on PaO2/FiO2 ratio at 24 h of
meeting acute respiratory distress syndrome criteria.
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Observational Model: Cohort, Time Perspective: Prospective
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