Effects of Physical Activity on Disease Risk Factors

Status Completed

Clinical Trial Summary

Obesity is associated with increased risk of heart disease and diabetes (Kim et al., 2010). Appalachian children in Athens County, Ohio, experience higher rates of obesity compared to the national average (20.9% vs. 15.4%), which increases their risk of obesity-related diseases (Montgomery-Reagan, Bianco, Heh, Rettos, & Huston, 2009). Although physical activity (PA) is known to improve fitness and adiposity (Gutin & Owens, 2011; Yin et al., 2009), very little is known about the effects of PA on the progression of chronic disease risk factors (biomarkers) for obesity-related diseases in children, such as inflammatory markers, lipids, and glucose/insulin. This lack of knowledge is due to a limited understanding of the number of calories burned during children's free-play PA. This study will assess the impact of a PA program (ACT) of known energy cost on obesity-related disease markers in 2nd-4th grade children compared to a sedentary control group (SED). The study will recruit children from an after-school program in Athens County elementary schools. Baseline and posttest data will include measures of height, weight, body composition, blood pressure, and physical activity levels. Following baseline measures, children will be randomized into either the ACT or SED group for 8 weeks. The ACT group will play recess-type games previously determined to expend ≥100 calories in 30 minutes. The SED group children will play sedentary-type activities during the same time period. It is hypothesized that the ACT group children will demonstrate significant improvements in PA after 8 weeks compared to the SED group children and that these improvements will be related to positive changes in body weight and body composition.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01849315
Study type	Interventional
Source	Ohio University
Contact
Status	Completed
Phase	N/A
Start date	September 2012
Completion date	March 2013

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT05437406` - Family, Responsibility, Education, Support, and Health for Latino Caregivers (FRESH-LC)	N/A
Completed	`NCT03297541` - Healthy Kids I-PAL	N/A
Completed	`NCT05527938` - Web-based Interventions on Nonalcoholic Fatty Liver Disease (NAFLD) in Obese Children	N/A
Completed	`NCT05501392` - South Texas Early Prevention Studies PreK	N/A
Completed	`NCT03334266` - Preventing Early Childhood Obesity, Part 2: Family Spirit Nurture, Prenatal - 18 Months	N/A
Active, not recruiting	`NCT03342092` - Early Adiposity Rebound Amongst 4-y.o. Children and Overweight Risk Amongst 11-y.o Children : Third Phase of a Cohort Study in Franche-Comté	N/A
Completed	`NCT06239662` - Therapeutic Education Groups for Childhood Obesity	N/A
Withdrawn	`NCT02767830` - Cleveland Kids Run	N/A
Not yet recruiting	`NCT02889406` - Motivation Approach for Childhood Obesity Treatment	N/A
Completed	`NCT03245164` - The Effects of Group Exercise and Basketball on Obese Children	N/A
Completed	`NCT02484976` - Brain Activation and Satiety in Children: Functional Magnetic Resonance Imaging	N/A
Completed	`NCT02559076` - The Eat Right Emirates Healthy Lifestyle Study	N/A
Completed	`NCT01977105` - Healthy Growth Abbreviated Pilot Study	N/A
Completed	`NCT02087774` - Brief Physical Activity Program to Increase Physical Fitness in Elementary School Children	N/A
Completed	`NCT01821313` - CASH- Children Active to Stay Healthy	N/A
Completed	`NCT01789671` - Peer Counseling in Family-Based Treatment for Childhood Obesity	N/A
Completed	`NCT02799433` - Evaluation of the Healthy Apple Program in San Francisco	N/A
Completed	`NCT02637752` - Nutrition and Physical Activity Counselling	N/A
Completed	`NCT01246349` - Motivational Interviewing for Weight Loss	N/A
Completed	`NCT00854334` - Co-existent Obstructive Sleep Apnea (OSA) and Obesity: Finding Non-exercise Activity Thermogenesis (NEAT) Targets for Intervention	N/A