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Clinical Trial Summary

This study's aim is to show a benefit of Cryocompression (cooling hands with additional compression of the hands) in comparison to Cryotherapy (just cooling hands) in female cancer patients (with gynecological cancer) receiving chemotherapy with taxanes. Patients who are not eligible for either cryocompression or cryotherapy are included in a control group. The expected benefits with additional compression to the cryotherapy are reduction of chemotherapy induced polyneuropathy and reduced nail changes.


Clinical Trial Description

In this randomized, observer blinded, monocentric study 196 patients will be included in a four years period. The patients will be 1 to 1 randomized in either cryocompression or cryotherapy. Patients who are not eligible for either cryocompression or cryotherapy will be included in the control group. Additionally every patient (excluding the control group) receives cryotherapy for the feet. Before receiving the first chemotherapy CTCAE, Semmes-Weinstein monofilament examination (SWME), vibration test for hand and feet, and nerve conduction velocity (NCV) only for hands. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04632797
Study type Interventional
Source Medical University Innsbruck
Contact Christine Brunner
Phone +4351250481194
Email c.brunner@tirol-kliniken.at
Status Recruiting
Phase N/A
Start date February 3, 2020
Completion date February 3, 2024

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