Chemotherapy-Induced Neutropenia Clinical Trial
Official title:
A Randomized, Open-Label, Single -Dose, Crossover, Phase I Clinical Trial to Evaluate the Effect of Food on the Safety, Tolerability and Pharmacokinetics of EC-18 After Oral Administration in Healthy Volunteers
A Randomized, Open-Label, Single -Dose, Crossover, Phase I Clinical Trial to Evaluate the Effect of Food on the Safety, Tolerability and Pharmacokinetics of EC-18 after Oral Administration in Healthy Volunteers
In vitro and in vivo efficacy studies and clinical trials have shown that EC-18 has a mode of
action of improving neutropenia by promoting neutrophil production from hematopoietic stem
cells and at the same time, efficiently controlling STAT6/Complement 3(C 3), suggesting its
potential to be developed as an orally administered new drug for treatment of neutropenia
resulting from decreased neutrophils caused by administration of an anticancer agent.
This study is a randomized, open-Label, single -dose, crossover, phase I clinical trial to
evaluate the effect of food on the safety, tolerability and pharmacokinetics of EC-18 after
oral administration in healthy volunteers
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