Multi-centre Study to Evaluate ACAF Versus Laminoplasty in Treating Cervical Ossification of the Posterior Longitudinal Ligament

Cervical Spondylosis With Myelopathy Clinical Trial

Official title:
An Open-label Randomized Multi-centre Study to Evaluate Anterior Controllable Antedisplacement and Fusion Versus Posterior Laminoplasty in Patients With Cervical Ossification of the Posterior Longitudinal Ligament

Status Recruiting

Clinical Trial Summary

The purpose of this study is to compare the efficacy, safety and imaging outcomes between Anterior Controllable Antedisplacement and Fusion (ACAF) and Laminoplasty in the treatment of severe ossification of cervical posterior longitudinal ligament.

Clinical Trial Description

This is a national, multicenter, prospective, randomized controlled trial to compare the safety and efficacy of ACAF and posterior laminoplasty in the treatment of severe ossification of cervical posterior longitudinal ligament. In this study, 164 adult patients aged 18-70 with severe copll were randomly assigned to the experimental group (using ACAF) and the control group (using lamp) according to the ratio of 1:1. The patients were followed up for 2 years. ;

Study Design

Related Conditions & MeSH terms

Bone Marrow Diseases
Cervical Spondylosis With Myelopathy
Ossification of Posterior Longitudinal Ligament
Spinal Cord Diseases
Spondylosis

Clinical Trial Details

NCT number	NCT04968028
Study type	Interventional
Source	Shanghai Changzheng Hospital
Contact	Dan Han, Master
Phone	+86 18317028536
Email	changzhengspine@163.com
Status	Recruiting
Phase	N/A
Start date	August 17, 2021
Completion date	December 31, 2026

View Details

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