Does Low-does Cervical Epidural Lidocaine Cause Transient Weakness?

Cervical Radiculopathy Clinical Trial

Official title: Do Cervical Interlaminar Epidural Steroid Injections With Low-dose Lidocaine Cause Transient Objective Upper Extremity Weakness? A Prospective Randomized

Status Terminated

Clinical Trial Summary

"Does low-does cervical epidural lidocaine cause transient weakness?"

Clinical Trial Description

Cervical radicular pain is relatively common, often treated with epidural steroid injection (ESI), when conservative treatments like oral analgesics, physical therapy, and activity modification have failed. There are no universal clinical practice guidelines for the use of diluents when CESI are performed.

Interlaminar CESI may be performed with or without the use of local anesthetics, due to training bias or theoretical concerns of weakness. CESI without the benefit of local anesthetic as a steroid diluent increases the latency of pain relief and may decrease diagnostic information immediately after a CESI with regard to pain generators responsible for symptoms, and may potentially decrease patient satisfaction.

By evaluating the effects of local anesthetic as a diluent during interlaminar cervical ESI, we will enhance the safety of this treatment with regard to expectations of objective motor weakness as well as post procedure pain control in the recovery phase after the injection procedure.

Additionally, investigation of short-term pain, function, medication use, and global impression of change following use of local anesthetic versus saline as a diluent during interlaminar cervical ESI will provide evidence to inform the optimization of clinical outcomes related to steroid diluent choice. ;

Related Conditions & MeSH terms

• Asthenia
• Cervical Radiculopathy
• Radiculopathy

• NCT number: NCT03382925
• Study type: Interventional
• Source: University of Utah
• Status: Terminated
• Phase: Phase 4
• Start date: December 20, 2017
• Completion date: August 19, 2020