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Clinical Trial Summary

External radiation given in 25 fractions or so together with weekly chemotherapy and followed by 5 or 6 fractions of brachytherapy is the standard of care for patients with locally advanced cervical cancer. We hope to develop external moderately hypofractionated radiotherapy of cervical cancer based on adaptive radiotherapy.The objective of this study is to evaluate the efficacy and treatment-related toxicity of moderately hypofractionated adaptive radiotherapy in the treatment of cervical cancer.


Clinical Trial Description

This is an investigator-initiated efficacious, single-center, open-label clinical trial study. This study hypothesizes that the use of external moderately hypofractionated radiotherapy of cervical cancer based on adaptive radiotherapy. A dose of 43.35Gy in 17 fractions is delivered to clinical target volume (CTV). Patients receive cisplatin based concurrent chemotherapy. The primary endpoint is acute toxicity. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05994300
Study type Interventional
Source Peking Union Medical College Hospital
Contact Fuquan Zhang, MD
Phone 86-10-6915-5485
Email Zhangfq@pumch.cn
Status Recruiting
Phase N/A
Start date September 19, 2023
Completion date December 31, 2025

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