Cervical Insufficiency Clinical Trial
Official title:
Role in Emergent Cerclage of Indomethacin and Antibiotics
Though cervical insufficiency is a common cause of second trimester pregnancy loss, the
placement of an emergent cerclage in these patients is thought to improve perinatal
outcomes. It is unknown whether the use of tocolytics and antibiotics prolongs pregnancies
complicated by need for emergent cerclage.
The objective is to determine whether administration of peri-operative antibiotics and
indomethacin to patients receiving emergent cerclages for cervical insufficiency increases
latency period to delivery compared with patients receiving emergent cerclage alone.
n/a
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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