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Clinical Trial Summary

The purpose of this research is to test the effectiveness and safety of the study drugs (VS-6766 and defactinib), and see what effects (good and bad) these drugs have on the patients with endometrioid cancer, mucinous ovarian cancer, high-grade serous ovarian cancer, or cervical cancer.


Clinical Trial Description

This is a single-stage exploratory, Phase 2, multicenter, parallel cohort, open label study designed to evaluate efficacy and safety of VS-6766 + defactinib. Enrolled study patients will receive the study drugs (VS-6766 and defactinib) to take orally based on the study procedures. Patients will follow the study procedures and attend all the study visits where various procedures including physical examinations, vitals, assessing the size of the patient's tumor, and examination of urine and blood may take place. Additional visits may be done to assess any other side effects a patient's experiences. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05512208
Study type Interventional
Source University of Oklahoma
Contact SCC IIT Office
Phone 4052718777
Email SCC-IIT-Office@ouhsc.edu
Status Recruiting
Phase Phase 2
Start date February 6, 2023
Completion date December 2029

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