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Individualized Antithrombotic Therapy for Patients With Ischemic Cerebrovascular Disease

Cerebrovascular Disease Clinical Trial

Official title:
Studies on the Individualized Prevention of Cerebrovascular Disease Using Study on Antithrombotic Therapy in Beijing

Clinical Trial Summary

To investigate the therapeutic effect of individualized treatment of antiplatelet in secondary prevention of ischemic stroke.

Clinical Trial Description

Ischemic stroke is a leading cause of disability and death worldwide. Antiplatelet treatment is one of treatment strategies in secondary stroke prevention for patients with non-cardioemoblism etiology. However, a concerning issue is that wide interindividual variability in P2Y12 antagonist, especially clopidogrel. The rate on-treatment high platelet reactivity (HPR) can be as high as in one-third of patients with standard dose of clopidogrel( i.e. 75mg), and HPR has been noted in those who received other P2Y12 antagonists, such as ticagrelor and prasugrel. In the present study, we aimed to investigate the safety and potential therapeutic effect of individualized treatment of antiplatelet in secondary prevention in a cohort of patients with non-cardioembolic ischemic strokes. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03471169
Study type Interventional
Source Xuanwu Hospital, Beijing
Contact Moli Wang, 1
Phone 13801234991
Email yifanhahahah@163.com
Status Recruiting
Phase Phase 1
Start date April 1, 2017
Completion date December 1, 2018
View Details
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