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Clinical Trial Summary

Cerebral radiation necrosis (CRN) is a well-documented late complication of radiation therapy for cancers, and may have a devastating effect on the patient's quality of life (QOL). However,CRN was once regarded as a progressive and irreversible disease, no standard therapy has been suggested for CRN. In our clinical practice, we have used nerve growth factor(NGF) to treat CRN, and found that GM1 can successfully reverse CRN. A case report has been published in Journal of Clinical Oncology (JCO) in 2011. So we carried out this prospective study to test the efficacy of NGF for CRN.


Clinical Trial Description

n/a


Study Design

Observational Model: Cohort, Time Perspective: Prospective


Related Conditions & MeSH terms


NCT number NCT02032147
Study type Observational
Source Fudan University
Contact
Status Completed
Phase N/A
Start date March 2009
Completion date October 2012

See also
  Status Clinical Trial Phase
Completed NCT02714465 - Adverse Radiation Effects After Gamma Knife Radio Surgery and Hyperbaric Oxygen Therapy N/A