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Clinical Trial Summary

The aim of this prospective study is to reveal the natural history of symptomatic hemorrhage in adult patients with cerebral cavernous malformation with the goal of informing the treatment plan.


Clinical Trial Description

Cerebral cavernous malformation Patients with newly diagnosed, cerebral cavernous malformation who will visit one of the study centers during the period from June 2016 to December 2017. Patients would be eligible for enrollment if they were 18 years of age or older and had at least 1 cerebral cavernous malformation. If the patient had multiple cavernous malformations, index cavernous malformation would be enrolled. Index lesion will be determined according to the criteria. - Index lesion decision criteria I. Symptomatic II. Asymptomatic (priorities are as follows) 1. Previous bleed 2. Brain stem location 3. Deep nuclei (thalamus, caudate, basal ggl, hypothalamus) 4. Periventricular 5. Largest All patients who would visit a study center during the enrollment period and meet these criteria will be asked to join the study. The cohort will consists of patients who agree to participate. Target population of this study is 228 patients. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02946866
Study type Observational
Source Seoul National University Hospital
Contact
Status Active, not recruiting
Phase
Start date June 2016
Completion date December 2024

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