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Clinical Trial Summary

In view of the synergistic effects of rituximab, zanubrutinib, and lenalidomide and severe complications caused by current standard chemotherapy regimens in Patients for primary or secondary CNS lymphoma, we intend to conduct a prospective clinical study to evaluate the efficacy and toxicity of Rituximab, Zanubrutinib in combination with Lenalidomide. Besides, the efficacy of Zanubrutinib or Lenalidomide in maintenance was also compared.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04938297
Study type Interventional
Source Henan Cancer Hospital
Contact Keshu Zhou, Dr.
Phone 13674902391
Email drzhouks77@163.com
Status Recruiting
Phase Phase 2
Start date May 26, 2021
Completion date December 31, 2025

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