Effectiveness of Efavirenz-based Regimen in HIV-1-infected Patients With Nevirapine Hypersensitivity

CD4 Cell Counts Clinical Trial

Official title: Comparison of Virological and Immunological Results of Efavirenz-based Regimen in HIV-infected Patients With or Without Allergic Reactions to Nevirapine

Status Completed

Clinical Trial Summary

The primary objective of this study is to compare the effectiveness of EFV-based regimens in HIV-1-infected patients who; (1) were previously allergic to NVP and stopped all ARV simultaneously; (2) were previously allergic to NVP and continued the other NRTIs for a period of time, i.e. "staggered interruption"; and (3) started EFV-based regimens as an initial regimen (as controlled group).

Clinical Trial Description

n/a

Study Design

Observational Model: Cohort, Time Perspective: Retrospective

Related Conditions & MeSH terms

• CD4 Cell Counts
• Treatment Failure, HIV or AIDS

• NCT number: NCT01044810
• Study type: Observational
• Source: Bamrasnaradura Infectious Diseases Institute
• Status: Completed
• Phase: N/A
• Start date: January 2010
• Completion date: March 2010