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Cataract clinical trials

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NCT ID: NCT03215186 Recruiting - Cataract Clinical Trials

Non-genetic Risk Factors of Congenital Cataracts

Start date: February 1, 2011
Phase: N/A
Study type: Observational

Prevention and treatment of the reversible childhood blindness, including congenital cataracts (CC), has been listed as a significant component of the international programme "VISION 2020 - the Right to Sight" launched by WHO in 1999. However, there is still a lot of unsolved problems regarding to CC, especially in developing countries, such as the delayed presentation and treatment to the hospitals, the lack of specialized treatment departments, and the poor treatment prognosis. With the two children policy opened in China in 2016, many CC parents hesitate to have a second child due to the potential high risk of CC. Date on detailed clinical characteristics of the CC children, including the demography, pregnancy-labor history, and living condition, are crucial for developing the national screening strategies of CC in Pregnant women. However, to our knowledge, it still lacks of thus large population-based and comprehensive investigations of the characteristics of CC children in developing countries.

NCT ID: NCT03206983 Completed - Cataract Clinical Trials

Efficacy of the Canabrava/s Pupil Expansion Device in Cataract Surgery With Small Pupils: The First 30 Cases

Start date: September 2014
Phase: N/A
Study type: Interventional

To evaluate the intraoperative stability, safety and overall efficacy of the Canabrava Ring (AJL - SPAIN) when used to expand pupils with less diameter than 5 mm and pupils with sphincter synechiae.

NCT ID: NCT03205202 Enrolling by invitation - Cataract Clinical Trials

Cataract and AMD in a Trial of a Multivitamin and Cocoa Extract

COSMOS-Eye
Start date: June 1, 2015
Phase: Phase 4
Study type: Interventional

COSMOS-Eye is an ancillary study of the COcoa-Supplement and Multivitamins Outcomes Study (COSMOS; NCT02422745). COSMOS is a randomized clinical trial of cocoa extract supplement (containing a total of 500 mg/d flavanols, including 80 mg (-)-epicatechins), and a standard multivitamin supplement to reduce the risk of cardiovascular disease and cancer among men aged 60 years and older and women aged 65 years and older. This ancillary study is being conducted among participants in COSMOS and will examine whether the cocoa extract supplement or the multivitamin supplement reduces the risk of cataract and AMD, two leading causes of visual impairment in US men and women.

NCT ID: NCT03192150 Completed - Clinical trials for Inflammation and Pain Associated With Cataract Surgery

2nd Study to Assess ISV-305 Compared to Vehicle for Treatment of Inflammation and Pain Associated With Cataract Surgery

ISV-305
Start date: January 3, 2018
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the ocular safety, tolerability, and efficacy of ISV-305 (Dexamethasone in DuraSite® 2) compared to Vehicle in the treatment of inflammation and pain associated with cataract surgery.

NCT ID: NCT03192137 Completed - Clinical trials for Inflammation and Pain Associated With Cataract Surgery

Study to Evaluate ISV-305 Compared to Vehicle for Treatment of Inflammation and Pain Associated With Cataract Surgery

ISV-305
Start date: January 30, 2018
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the ocular safety, tolerability, and efficacy of ISV-305 (dexamethasone in DuraSite® 2) compared with Vehicle in the treatment of inflammation and pain associated with cataract surgery.

NCT ID: NCT03184428 Completed - Clinical trials for Posterior Capsule Opacification

Posterior Capsule Opacification Following Cataract Surgery With Implantation of the MICS IOL L313

Start date: October 1, 2015
Phase:
Study type: Observational

This study collects intra- and postoperative data from the patients´charts retrospectively and evaluates retro- and prospectively the rate of posterior capsule opacification (PCO) following implantation of the intraocular lens L 313.

NCT ID: NCT03180255 Completed - Pain, Postoperative Clinical Trials

Iontophoretic Delivery of EGP-437 in Patients Who Have Undergone Cataract Surgery

Start date: July 26, 2017
Phase: Phase 2
Study type: Interventional

Phase 2b trial evaluating the safety and efficacy of EGP-437, versus placebo using the EyeGate® II Drug Delivery System (EGDS) in patients having undergone cataract surgery with implantation of a monofocal posterior chamber intraocular lens (IOL).

NCT ID: NCT03179397 Terminated - Cataract Clinical Trials

Clinical Trial to Evaluate the Model SC9 IOL Compared to the Model LI61SE IOL (Bausch & Lomb)

Start date: May 31, 2017
Phase: N/A
Study type: Interventional

To evaluate the Model SC9 Intraocular Lens for the improvement of near and intermediate vision when compared to a legally marketed monofocal IOL.

NCT ID: NCT03172351 Completed - Cataract Clinical Trials

EDoF IOLs vs Monofocal IOL

Start date: May 24, 2017
Phase: N/A
Study type: Interventional

prospective, comparative (3 arms), randomized, multicentric clinical trial

NCT ID: NCT03170154 Completed - Cataract Clinical Trials

Clinical Investigation of the Clareon® Intraocular Lens (IOL)

Start date: July 25, 2017
Phase: N/A
Study type: Interventional

The objective of this study is to compare visual acuity and adverse event outcomes from the Clareon intraocular lens (IOL) to historical safety and performance endpoint (SPE) rates.