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Cataract clinical trials

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NCT ID: NCT04077489 Completed - Congenital Cataract Clinical Trials

Effects of 23-gauge Lensecotomy Combined With Anterior Vitrectomy on Macular in Children With Congenital Cataract

Start date: January 2016
Phase: N/A
Study type: Interventional

Congenital cataract is the main cause of form deprivation amblyopia in children. Current studies confirm that form deprivation amblyopia affects the macular development. However, there are different opinions about the effect of amblyopia on the macular thickness . Investigators have performed "cataract extraction with IOL implantation" on children with bilateral and unilateral congenital cataract. Investigators used OCT biometry to measure children's the macular thickness before and after surgery..Average sectional total thickness was automatically determined by the instrument's software using a modified Early Treatment Diabetic Retinopathy Study (ETDRS) circle grid (fovea, inner ring, and outer ring: 1 mm, 3 mm, and 6 mm. Investigators dynamically observed changes in macular to explore the retinal mechanism of form deprivation amblyopia and help guide the clinical correct understanding of postoperative follow-up time.

NCT ID: NCT04074954 Withdrawn - Obesity Clinical Trials

A (Prospective/Pilot) Study Evaluating the Effect of Cataract Surgery on the Daily Activity Levels of Elderly Patients

Start date: March 23, 2023
Phase:
Study type: Observational [Patient Registry]

To evaluate the effect of bilateral cataract surgery with intraocular lens implantation on the daily activity levels of elderly patients.

NCT ID: NCT04072029 Completed - Cataract Clinical Trials

Risk Assessment for Progression to DMEK Following Cataract Surgery in Fuchs Endothelial Corneal Dystrophy

Start date: July 1, 2017
Phase:
Study type: Observational

Justification. Fuchs' corneal endothelial dystrophy (FECD) is one of the main causes of corneal transplantation. In many cases, the corneal decompensation derived from this dystrophy is triggered as a consequence of cataract surgery, so the dilemma of facing isolated cataract surgery or combined with endothelial keratoplasty is often raised. Objective. The present study aims to evaluate and select the most important predictive factors for corneal decompensation after cataract surgery in patients with FECD. Method. Prospective observational study of the preoperative and intraoperative variables presumably associated with postoperative corneal edema requiring Descemet stripping endothelial keratoplasty (DMEK). Consecutive candidates for cataract surgery with FECD will be selected and anterior segment imaging will be performed, along with a complete ophthalmological examination. Clinical, pachymetric, tmographic, densitometric, specular microscopy, and intraoperative variables will be registered.

NCT ID: NCT04067856 Withdrawn - Cataract Clinical Trials

Intravitreal Dexamethasone Implant (Ozurdex) Versus Bevacizumab in Patients With Diabetic Macular Edema Undergoing Cataract Surgery

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

The purpose of this research is to compare the effectiveness of bevacizumab (Avastin) with another a dexamethasone implant (Ozurdex), with respect to anatomic and visual outcomes as well as injection frequency in subjects undergoing cataract surgery with a concurrent diagnosis of diabetic macular edema (DME).

NCT ID: NCT04063644 Completed - Cataract Clinical Trials

Quality of Life and Visual Acuity of Visglyc Eye Drops on Dry Eye Patients

Start date: May 30, 2019
Phase: N/A
Study type: Interventional

Clinical trial with medical devices, post-authorization, parallel, single-blind, randomized, comparative, prospective to study how afects the quality of life the use of ocular eye drops on patients with dry eye symptomatology and age-related loss of visual acuity. Secondary purposes: efects on the dry eye symptomatology, efect on visual acuity and treatment adherence.

NCT ID: NCT04063358 Recruiting - Cataract Clinical Trials

Anti-VEGF Intravitreous Injections for Diabetic Macular Edema in Patients Undergoing Cataract Surgery

Anti-VEGF
Start date: August 22, 2019
Phase: Phase 3
Study type: Interventional

The investigators aim to evaluate how different timing of anti-VEGF intravitreous injections affect visual acuity (BCVA) in patients with diabetic macular edema who are undergoing cataract surgery; and to evaluate how different timing of anti-VEGF intravitreous affect OCT CSF thickness and total number of postoperative injections in patients with diabetic macular edema who are undergoing cataract surgery.

NCT ID: NCT04062084 Active, not recruiting - Subluxation of Lens Clinical Trials

Study of Multifunctional Cataract-assisted Retractor in Complicated Cataract Surgery

Start date: September 1, 2019
Phase: N/A
Study type: Interventional

To compare the safety and efficacy of a new multi-functional cataract-assisted surgical instrument with that of traditional cataract-assisted surgical instrument in cataract surgery with subluxation of lens.

NCT ID: NCT04059796 Completed - Cataract Clinical Trials

Comparison of Gemini III Rev 2 Implanted in Conjunction With an Approved IOL vs Eyes Implanted With an Approved IOL

Start date: February 21, 2020
Phase: N/A
Study type: Interventional

This study is a prospective, observational, randomized, controlled, paired eye, subject-masked design.

NCT ID: NCT04058314 Completed - Cataract Clinical Trials

Clinical Investigation of OMEGA Gemini Capsule, Model Gemini IV With an Approved Monofocal or Toric IOL

Start date: February 21, 2020
Phase: N/A
Study type: Interventional

This study is a prospective, randomized, controlled, paired eye, subject-masked design.

NCT ID: NCT04057053 Completed - Cataract Clinical Trials

Netarsudil Use After Descemetorhexis Without Endothelial Keratoplasty

Start date: October 2, 2018
Phase: Early Phase 1
Study type: Interventional

Primary aim of the study is to determine whether a rho kinase inhibitor, Netarsudil, can speed corneal clearance after DWEK. Secondary aim of the study is to investigate whether patient factors, such as baseline age, pachymetry, or endothelial cell count influence response to Netarsudil.