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Cataract clinical trials

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NCT ID: NCT00612781 Completed - Cataract Clinical Trials

Yellow Versus White Study

YeWhi
Start date: December 2005
Phase: Phase 4
Study type: Interventional

Blue-light-filtering IOLs are implanted increasingly often in cataract surgery. Several studies examined the effect of blue-light-filters on contrast and colour vision. However, the study outcomes were varying. The present study investigated the effect of a blue-light-filtering IOL on colour perception and contrast acuity using highly sensitive measurement methods.

NCT ID: NCT00612729 Completed - Cataract Clinical Trials

Light Filters in Intraocular Lenses (IOLs) and Its Influence on Colour and Contrast Vision.

Start date: May 2008
Phase: Phase 4
Study type: Interventional

Visible-light-filtering IOLs are implanted increasingly often in cataract surgery. Several studies examined the effect of light-filters on contrast and colour vision. However, the study outcomes were varying. The present study investigated the effect of two light-filtering IOL on colour perception and contrast acuity using highly sensitive measurement methods.

NCT ID: NCT00596583 Completed - Mature Cataracts Clinical Trials

DY001: Safety and Effectiveness of DYME as an Agent for Selective Staining of the Anterior Capsule During Cataract Surgery

Start date: April 2007
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to test the hypothesis that DYME is safe and effective as a drug to facilitate continuous curvilinear capsulorhexis (CCC) by selectively staining the anterior capsule. Secondary objectives are to compare the safety and effectiveness of DYME to that of a smaller dose of the same API.

NCT ID: NCT00596492 Terminated - Mature Cataracts Clinical Trials

DY002: Safety and Effectiveness of DYME as an Agent for Selective Staining of the Anterior Capsule During Cataract Surgery

AQNA-DY002
Start date: May 2008
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to test the hypothesis that DYME is safe and effective as a drug to facilitate continuous curvilinear capsulorhexis (CCC) by selectively staining the anterior capsule. Secondary objectives are to compare the safety and effectiveness of DYME to that of a smaller dose of the same API.

NCT ID: NCT00594672 Active, not recruiting - Cataract Clinical Trials

Age-Related Eye Disease Study (AREDS) Follow-Up

Start date: June 2, 2008
Phase:
Study type: Observational

This study is a 5-year extension of the AREDS protocol, in which investigators followed the natural course of age-related macular degeneration (AMD) and cataracts. Participants in the former AREDS protocol are eligible for this study. Participants have a complete eye examination once a year and are contacted at least once a year between visits to check on their status. The eye examination includes measurement of visual acuity (vision chart test) and examination of the inside of the eye after the pupils have been dilated with eye drops. Photographs of the inside of the eye may be taken using a special camera that flashes a bright light in the eye. A blood sample may be obtained to test for cholesterol level and genes related to inflammation....

NCT ID: NCT00576485 Completed - Cataract Clinical Trials

Spherical Aberration and Contrast Sensitivity in IOLs

IOLs
Start date: February 2005
Phase: Phase 4
Study type: Interventional

Purpose: To determine whether implantation of an intraocular lens (IOL) with a modified anterior aspheric surface results in reduced spherical aberration and improved contrast sensitivity after cataract surgery. Design: Prospective, comparative, interventional case series. Methods: In an intraindividual randomized prospective study of 25 patients with bilateral cataract, an IOL with a modified anterior surface (Tecnis Z9001, AMO- Group 1) was compared with biconvex lens with spherical surfaces (ClariFlex®, AMO- Group 2). Ocular aberrations for a 5.0 mm pupil and 6.0 mm pupil were measured with Hartmann-Shack aberrometer. Quality of vision was measured by visual acuity and contrast sensitivity under mesopic and photopic conditions. All patients were followed for 3 months.

NCT ID: NCT00575380 Completed - Clinical trials for Bacterial Infections

Study of AzaSite Versus Vigamox Concentrations in the Conjunctiva and Aqueous Humor in Subjects Undergoing Routine Cataract Surgery

Start date: December 2007
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the drug concentrations in the conjunctiva and aqueous humor of AzaSiteā„¢ compared to Vigamox® in subjects undergoing routine cataract surgery

NCT ID: NCT00571831 Completed - Clinical trials for on the Incidence of Cystoid Macular Edema

The Effect of a Blue Light Filtering IOL

Start date: February 2003
Phase: N/A
Study type: Interventional

To compare the effect on blood retinal barrier disruption 3 and 12 months after implantation of either a blue light filtering intraocular lens(blue-filtering IOL) or an ultraviolet light filtering intraocular lens(UV-filtering IOL).

NCT ID: NCT00565695 Completed - Cataract Extraction Clinical Trials

Evaluation of the Aspheric ReSTOR Intraocular Lens (IOL) After Routine Cataract Extraction

Start date: October 2007
Phase: N/A
Study type: Observational

The purpose of this study is to evaluate the visual outcomes and patient satisfaction after bilateral implantation of the aspheric ReSTOR multifocal intraocular lens (IOL) and compare it to a historical control group of patients implanted bilaterally with the spherical ReSTOR multifocal IOL.

NCT ID: NCT00565630 Withdrawn - Cataract Clinical Trials

Using Device Delivering Ophthalmic Solution in a Spray Form Instead of Eye Drops

Start date: January 2008
Phase: N/A
Study type: Interventional

The purpose of the study is to confirm that Vigamox reaches similar aqueous concentration when administered as the commercially available eye drops or as a spray delivered from a proprietary device.