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Cataract clinical trials

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NCT ID: NCT01109173 Completed - Cataract Clinical Trials

Confirmatory Study Nepafenac 0.3%

Start date: June 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study was to assess the safety and efficacy of an investigational eye drop intended for the prevention and treatment of inflammation (swelling and redness) and pain in the eye after cataract extraction.

NCT ID: NCT01103401 Completed - Cataract Clinical Trials

Ketorolac Plus Tobramycin/Dexamethasone Versus Tobramycin/Dexamethasone After Uneventful Phacoemulsification Surgery

Start date: October 2009
Phase: N/A
Study type: Interventional

This randomized controlled trial compares two regimens of topical therapy: - tobramycin 0.3% - dexamethasone 0.1% (TobraDex®, Alcon), one drop four times/day - combination of tobramycin 0.3% - dexamethasone 0.1% (TobraDex®, Alcon), one drop four times/day, plus Ketorolac tromethamine 0.5% (Acular®, Allergan), one drop three times/day. Patients are independently assessed by two ophthalmologists. On days 7,14,21,28 patients are evaluated for - corneal edema - conjunctival hyperemia - anterior chamber (Tyndall) reaction. The investigators purpose was to evaluate the benefit of adding a non-steroid agent to an antibiotic/steroid combination after uneventful phacoemulsification. Adopting a weekly follow-up, to gain insight into the optimal duration of postoperative treatment and to examine whether risk factors for inflammation exist.

NCT ID: NCT01098812 Completed - Cataract Clinical Trials

Clinical Evaluation of a 1-Piece Intraocular Lens

Start date: March 2010
Phase: Phase 3
Study type: Interventional

The aims of this study are to: - Demonstrate a reduction in postoperative cylinder compared to results from the control lens - Demonstrate better uncorrected distance visual acuity compared to the control lens

NCT ID: NCT01085357 Completed - Cataract Clinical Trials

Study of an Implantable Device for Lowering Intraocular Pressure in Glaucoma Patients Undergoing Cataract Surgery

COMPASS
Start date: September 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of the CyPass Implant for lowering intraocular pressure (IOP) in patients with glaucoma who undergo cataract surgery.

NCT ID: NCT01078103 Completed - Diabetes Clinical Trials

Corneal Endothelial Changes Associated With Phacoemulsification in Diabetes Mellitus Type II

Start date: July 2005
Phase: Phase 4
Study type: Observational

Some studies indicated that the diabetic corneal endothelium is morphologically abnormal and may be at risk in any intraocular surgical procedure, while others showed no significant differences between diabetic and non-diabetic corneal endothelium.The purpose of this study is to investigate the differences in corneal endothelial cell density and morphology in diabetic patients and normal patients after phacoemulsification with intraocular lens implantation.To investigate if haemoglobin A1c can be used as a predictor of corneal endothelial cell changes after phacoemulsification.

NCT ID: NCT01076309 Completed - Cataract Clinical Trials

Corneal Endothelium Cell Loss After Cataract Extraction in Patients Taking Tamsulosin

Start date: June 2009
Phase: N/A
Study type: Observational

The purpose of this study is to determine whether corneal endothelium cell loss during cataract surgery is higher in patients taking Tamsulosin.

NCT ID: NCT01074606 Terminated - Cataract Clinical Trials

Visual Function After Implantation of AcrySof® Toric Lens

Start date: January 2010
Phase: Phase 4
Study type: Interventional

The objective of this study is to evaluate the postoperative visual function of Taiwanese patients following bilateral or unilateral AcrySof Toric Intraocular Lens (IOL) implantation.

NCT ID: NCT01069341 Completed - Clinical trials for Proliferative Diabetic Retinopathy

Use of Ranibizumab to Treat Rubeosis in Diabetics Prior to Cataract Surgery

Start date: July 2007
Phase: Phase 1
Study type: Interventional

The purpose of this study was to determine the safety of ranibizumab: a) as a surgical adjunct during cataract surgery in subjects with proliferative diabetic retinopathy (PDR) induced rubeosis and, b) in treatment of proliferative diabetic retinopathy (PDR).

NCT ID: NCT01069172 Completed - Cataract Clinical Trials

Study of the Femtosecond Laser System as Compared to Continuous Curvilinear Capsulorhexis for Cataract Surgery

Start date: February 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of the OptiMedica Femtosecond Laser System to perform surgical maneuvers used in the treatment of subjects with cataracts. The safety and efficacy will be compared to the standard surgical procedure of continuous curvilinear capsulorhexis (CCC) and ultrasonic phacoemulsification.

NCT ID: NCT01069029 Completed - Visual Acuity Clinical Trials

Combined Versus Successive Macular Hole and Cataract Surgery

Start date: January 2006
Phase: N/A
Study type: Observational

The purpose of this study is to compare functional and anatomical results of a combined surgery and two time surgery for macular hole and cataract extraction in one hundred and twenty patients (120 eyes) with idiopathic Macular Hole (MH) and cataract in two academic centers.