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Cataract clinical trials

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NCT ID: NCT01996839 Completed - Pain Clinical Trials

Loteprednol Ophthalmic Gel for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery

Start date: December 2013
Phase: Phase 3
Study type: Interventional

The objective of this study is to evaluate the safety and efficacy of loteprednol etabonate ophthalmic gel

NCT ID: NCT01995630 Completed - Cataract Clinical Trials

Optical Quality After Implantation of a Spherical or Aspherical Intraocular Lens in Hypermetropic Patients

Start date: November 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate differences in the depth of focus after implantation of a spherical or aspheric IOL in hypermetropic and emmetropic patients. After implantation of a spherical IOL hypermetropic patients may achieve a better depth of focus compared to emmetropic patients due to a larger amount of spherical aberrations.

NCT ID: NCT01991717 Recruiting - Cataract Clinical Trials

Victus Versus Conventional

Start date: December 2013
Phase: N/A
Study type: Interventional

Cataract surgery is among the world's most frequently performed operations. It involves removal of an opaque lens from the human eye and implantation of an artificial lens. The operation is performed under local anaesthesia using ultrasound technology, by which the lens is emulsified and removed by suction. Femtosecond laser-assisted cataract surgery is a new innovative surgical procedure that can improve the quality of cataract surgery and provide a new best possible standard of quality. In contrast to the conventional method the capsulotomy and the fragemntation are fully automatically performed with a femtosecond laser. In addition, the lens is fragmented by the laser, which substantially facilitates its removal and reduces the operation time. Study to investigate whether the femtosecond laser cataract surgery causes any significant differences in clinical outcomes as compared to the conventional, manual continuous curvilinear capsulorhexis (CCC). Effective phako time (EPT) is defined as duration of phakoemulsifikation of the crystalline lens. EPT of conventional surgery at intraoperative visit > EPT oflaser-assisted surgery at intraoperative visit

NCT ID: NCT01988246 Completed - Clinical trials for Diabetic Retinopathy

Prevention of Macular Edema In Patients With Diabetic Retinopathy Undergoing Cataract Surgery

PROMISE
Start date: December 2013
Phase: Phase 1/Phase 2
Study type: Interventional

To determine the safety and efficacy of intravitreal Aflibercept (Eylea) injection in patients with diabetic retinopathy in the prevention of macular edema following cataract surgery.

NCT ID: NCT01982006 Completed - Cataract Clinical Trials

Economic Evaluation of Femtosecond Laser Assisted Cataract Surgery

FEMCAT
Start date: October 9, 2013
Phase: Phase 3
Study type: Interventional

Cataract is the leading cause of blindness worldwide and cataract surgery is the most frequent surgery performed in France. A new technology, the femtosecond laser-assisted cataract surgery, has to be compared with phacoemulsification alone, the conventional cataract surgery, to determine the economic impact of femtosecond laser-assisted process for the French healthcare insurance.

NCT ID: NCT01979172 Recruiting - Cataract Clinical Trials

Comparison of Intraocular Lens Power Calculation Methods After Corneal Laser Refractive Surgery in Axial and Refractive Ammertropia

Start date: November 2013
Phase: N/A
Study type: Observational

The study aims at determining the best biometry calculation formula to be used in IOL calculation of cataract patients how previously underwent laser refractive correction surgery

NCT ID: NCT01978106 Completed - Cataract Clinical Trials

Comparisons of the Astigmatic Power of Toric Intraocular Lens Using Three Toric Calculators: AcrySof, TECNIS, and iTrace Toric Calculator

Start date: January 2013
Phase: N/A
Study type: Observational

Purpose of this study is to compare the astigmatic power of the toric IOL obtained from the AcrySof toric calculator, TECNIS toric calculator, and iTrace toric calculator in a group of patients with preoperative with-the-rule (WTR) and against-the-rule (ATR) corneal astigmatism. The study included 100 eyes with cataract and greater than 0.75 diopter of corneal astigmatism, and the subjects were divided into WTR and ATR group. Keratometric value was measured using autokeratometry, IOLMaster partial coherence interferometry (PCI), iTrace incorporating corneal topography and ray-tracing aberrometry. Based on measured values, toric IOL power calculations were performed using AcrySof, TECNIS and iTrace toric calculators.

NCT ID: NCT01971177 Completed - Cataract Clinical Trials

Addressing of Efficacy and Safety of Femtosecond-laser Assisted Versus Manual Lens Fragmentation Procedure

Start date: October 2013
Phase: Phase 4
Study type: Interventional

This clinical study is a randomized, controlled, open, prospective, multi-centre, multi-surgeon post-market-clinical-follow-up study to investigate the impact of cataract grade on the efficacy and safety of femtosecond laser assisted lens fragmentation to support phacoemulsification of the cataractous lens prior to intraocular lens (IOL) implantation.

NCT ID: NCT01961089 Completed - Cataract Clinical Trials

Galilei Lens Professional vs. Predicate Devices: a Comparison Study

Start date: October 2013
Phase: N/A
Study type: Interventional

Study question: How does the new GALILEI Lens Professional compare to predicate devices? Study hypothesis: The GALILEI Lens Professional achieves a better precision in the postoperative, calculated target refraction with cataract surgeries than predicate devices, and it is more versatile in the measurable parameters as well as more user-friendly.

NCT ID: NCT01946581 Recruiting - Cataract Clinical Trials

Retrospective Patient Satisfaction Survey in Subjects With Tecnis Intra Ocular Lenses and Cataracts Surgery

Start date: May 2013
Phase: N/A
Study type: Observational

Define what factors correlate with higher degrees of patient satisfaction and dissatisfaction among patients who have recently undergone cataract surgery.