Clinical Trials Logo

Clinical Trial Details — Status: Enrolling by invitation

Administrative data

NCT number NCT05578963
Other study ID # FRC-BUMDC35/2021
Secondary ID
Status Enrolling by invitation
Phase
First received
Last updated
Start date October 15, 2022
Est. completion date December 1, 2023

Study information

Verified date July 2023
Source Bahria University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The Palmaris longus (PL) muscle is a long, adaptable muscle that lies between the Flexor Carpi Ulnaris and Flexor Carpi Radialis muscles in the shallow volar segment of the lower arm. It has been acknowledged as a minimal muscle, nonetheless, in light of the fact that reviews have uncovered that around 30% of the populace might be feeling the loss of this muscle in one lower arm (one-sided) or the two lower arms (reciprocal), but the rate could continuously fluctuate. Carpal tunnel syndrome is an often-observed disease that causes pain, numbness, and tingling in the hand and arm. The disease occurs when one of the major nerves to the hand - the median nerve - is compressed as it moves across the wrist. The abnormal passage of palmaris longus tendon through the carpal tunnel leads to a contributory factor for causing the median nerve compression.


Description:

The Palmaris longus (PL) muscle is a long, adaptable muscle that lies between the Flexor Carpi Ulnaris and Flexor Carpi Radialis muscles in the shallow volar segment of the lower arm. It has been acknowledged as a minimal muscle, nonetheless, in light of the fact that reviews have uncovered that around 30% of the populace might be feeling the loss of this muscle in one lower arm (one-sided) or the two lower arms (reciprocal), but the rate could continuously fluctuate. Agenesis is a typical physical variety. Hold strength is unaffected by the deficiency of the palmaris longus. Past examination has assessed that 15% of the worldwide populace has palmaris longus ligament agenesis (PLA), which is more successive in ladies and has an affinity to be higher respectively however, if present singularly, is normally on the left side. It emerges from the Medial Epicondyle of the Humerus and goes into the Palmar Aponeurosis and Flexor Retinaculum at the wrist joint through the normal flexor ligament. It accepts its innervation from the Median Nerve. Palmaris longus works couple with the lower arm's long flexors to give flexion at the wrist joint and small joints of the hand. The muscle additionally helps in fixing and worrying the palmar aponeurosis. Carpal tunnel syndrome is an often-observed disease that causes pain, numbness, and tingling in the hand and arm. The disease occurs when one of the major nerves to the hand - the median nerve - is compressed as it moves across the wrist. The abnormal passage of palmaris longus tendon through the carpal tunnel leads to a contributory factor for causing the median nerve compression. The tendinous structure normally passes anterior to the flexor retinaculum and then distally continues with the palmar aponeurosis. This topographic relationship of the tendon with the median nerve makes its anatomical variations a common cause of median nerve entrapment. Several anatomical variations of the PL muscle have been studied in the past. The variations could be in the form of complete absence, insertion site variation, multiple muscle bellies, different location of the muscle belly, and so on.


Recruitment information / eligibility

Status Enrolling by invitation
Enrollment 258
Est. completion date December 1, 2023
Est. primary completion date February 25, 2023
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 23 Years
Eligibility Inclusion Criteria: - Health profession Students with carpel tunnel syndrome across Pakistan - Age should be 18-23 years Exclusion Criteria: - Students who had carpel tunnel release surgery - Any wrist related pathology - Involve in any other wrist related research - Underwent any surgery of wrist - Underwent any surgery that required replacement of tendon - Underwent any surgery that had Palmaris longus tendon for replacement

Study Design


Related Conditions & MeSH terms


Intervention

Other:
Schaeffer's Test for palmaris tendon
After demographics, Schaeffer's Test will be used to check the presence or absence of palmaris longus muscle. In this test, students will maintain the forearm at 90 degrees first followed by moving the thumb in opposition towards the little finger with the wrist partially flexed. If the tendon bulges out, it will reflect presence of palmaris longus and vice versa. This finding will be recorded. After that, students will perform Phalen's test. In this test, researcher will ask them to press the backs of their hands and fingers together with their wrists flexed and fingers pointed down. they'll stay that way for a minute or two. If fingers tingle or get numb, it will indicate carpal tunnel syndrome. The reading will be recorded.

Locations

Country Name City State
Pakistan Seyyada Tahniat Ali Karachi Sindh

Sponsors (1)

Lead Sponsor Collaborator
Bahria University

Country where clinical trial is conducted

Pakistan, 

References & Publications (3)

Clinical Assessment of the Palmaris Longus - Accuracy of common tests Authors: Kigera JWM1 MBChB, MMed (Ortho), Mukwaya S2 Affiliation

Mohammad WS. Work-related risk factors for Carpal Tunnel Syndrome among Majmaah University female touchscreen users. Pak J Med Sci. 2019 Sep-Oct;35(5):1221-1226. doi: 10.12669/pjms.35.5.683. — View Citation

Priganc VW, Henry SM. The relationship among five common carpal tunnel syndrome tests and the severity of carpal tunnel syndrome. J Hand Ther. 2003 Jul-Sep;16(3):225-36. doi: 10.1016/s0894-1130(03)00038-3. — View Citation

Outcome

Type Measure Description Time frame Safety issue
Primary correlation of palmaris longus tendon and carpel tunnel syndrome The first test developed in 1909. It Involves maintaining the forearm at 90 degrees first followed by moving the thumb in opposition towards the little finger with the wrist partially flexed. The building tendon represents the presence of palmaris longus muscle.The practitioner will tell you to press the backs of your hands and fingers together with your wrists flexed and your fingers pointed down. You'll stay that way for a minute or two. If fingers tingle or get numb, it indicates carpal tunnel syndrome 1 day
See also
  Status Clinical Trial Phase
Completed NCT05067205 - Minimal Invasive Carpal Tunnel Release With the Novel Device N/A
Completed NCT03184688 - Platelet Rich Plasma for Carpal Tunnel Syndrome N/A
Completed NCT03582735 - Preoperative Neuromobilization Exercises for Individuals With Carpal Tunnel Syndrome N/A
Completed NCT05490420 - Effects of Upper Extremity Manual Lymphatic Drainage on Symptom Severity, Hand Functions, Electrophysiological and Ultrasonographic Measurements in Carpal Tunnel Syndrome N/A
Recruiting NCT05970692 - Cross-Cultural Adaptation and Psychometric Validation of the Turkish Version of Atroshi-Lyrén 6-item Symptoms Scale
Completed NCT04043780 - Clinical Validation of a Decompression Prototype Splint for Patients With Carpal Tunel Syndrome N/A
Completed NCT03880812 - Cost Information on Carpal Tunnel Syndrome Treatment Decisions N/A
Completed NCT06464809 - Treatment Intervention of Patients With Carpal Tunnel Syndrome (CTS) N/A
Recruiting NCT05328180 - aDjunct bicarbonatE in Local anaesthesIa for CarpAl Tunnel rElease (DELICATE) N/A
Recruiting NCT05503719 - An Absorbable Suture Versus a Non-absorbable Suture in Carpal Tunnel Release, a Randomized Controlled Trial N/A
Recruiting NCT05372393 - Carpal Tunnel Release Under Local Anaesthesia With or Without Distal Median Nerve Block N/A
Recruiting NCT05466162 - Soft Tissue Massage Along With Mobilization Technique on Symptoms and Functional Status of Carpal Tunnel Syndrome N/A
Completed NCT04060875 - Research Protocol for Karuna Labs Inc.: Safety and Efficacy of Virtual Reality Graded Motor Imagery for Chronic Pain
Not yet recruiting NCT06294821 - 4AP to Delay Carpal Tunnel Release (CTR) Phase 2/Phase 3
Not yet recruiting NCT04328805 - Pain Reduction and Changes in Upper Limb Function Produced by an Ibuprofen Treatment in Carpal Tunnel Syndrome. Phase 4
Terminated NCT02791529 - Scalpel Versus Electrocautery for Surgical Skin Incision in Open Carpal Tunnel Release Phase 1
Completed NCT02141035 - Acetyl-l-carnitine to Enhance Nerve Regeneration in Carpal Tunnel Syndrome Phase 2/Phase 3
Completed NCT01887145 - Comparison of Long-term Outcomes Following Endoscopic or Open Surgery for Carpal Tunnel Syndrome N/A
Recruiting NCT01897272 - Post-Operative Splinting After Short-Incision Carpal Tunnel Release: a Prospective Study N/A
Completed NCT01394822 - Neuromuscular Ultrasound for Focal Neuropathies N/A