Intraneural Facilitation as a Treatment for Carpal Tunnel Syndrome

Status Completed

Clinical Trial Summary

We hypothesize that a standard course of INF can result in significant improvement in CTS as measured by clinical, electrodiagnostic, or ultrasound measures.

Clinical Trial Description

INF is a novel non-invasive therapy based on the principle of restoring vascular function at the capillary level in peripheral nerve. his therapy has been shown to improve clinical function in patients with diabetic-associated polyneuropathy, a model for various forms of ischemic neuropathy. CTS is a common condition where regional compression at the wrist results in ischemic focal demyelination of the distal median nerve. This results in sensory dysfunction, pain, and eventually axon loss and weakness if the compression is sufficiently severe and prolonged. Standard therapy for CTS includes wrist splints, regional lidocaine injections, ergonomic adjustments, various forms of occupation therapy, and ultimately surgical release of the carpal tunnel ligament. However, all of these are either temporary in their effect or invasive. The diagnosis of CTS relies on clinical, electrodiagnostic or NCS, and ultrasound methods. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03205683
Study type	Interventional
Source	Loma Linda University
Contact
Status	Completed
Phase	N/A
Start date	January 29, 2018
Completion date	February 22, 2019

View Details

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