Carpal Tunnel Syndrome Clinical Trial
Official title:
BOTOX® (Onabotulinumtoxin A) Injection(s) as a Treatment for Carpal Tunnel Syndrome
This study will be a prospective double blind controlled randomized trial of ten patients diagnosed with Carpal Tunnel Syndrome (CTS). The study will be completed at offices of medical practices in Arizona. Patients who meet inclusion criteria will be randomly distributed into two groups: a BOTOX® (onabotulinumtoxin A) injection group and a Normal Saline Injection (NS) (Placebo group). Each group will consist of five randomly assigned individuals.
This is a pilot study, to assist with determining appropriate BOTOX® (onabotulinumtoxin A)
dosing and injection locations in patients suffering from CTS.
Outcome measures will be obtained at follow-up at 6, 12, and 18 weeks post BOTOX®
(onabotulinumtoxin A) injection and post saline injection using the same scales and
instruments at baseline, namely Levine scale, JAMAR pinch dynamometer, EDX/NCS and NMUS.
These measurements will be used to identify the effectiveness of BOTOX® (onabotulinumtoxin A)
in decreasing thenar muscle strength, appropriate BOTOX® (onabotulinumtoxin A) injection
dosing, and ability to decrease the inflammation, median nerve dysfunction, edema, symptoms
of pain, numbness, and tingling often with associated with CTS.
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