Carpal Tunnel Syndrome: Case Reports and Analysis - Ultrasound Imaging and Pathomechanics of Median Nerve Compression

Carpal Tunnel Syndrome Clinical Trial

Official title:

Carpal Tunnel Syndrome: Case Reports and Analysis - Ultrasound Imaging and Pathomechanics of Median Nerve Compression

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00987571
• Other study ID #: CTS-US Med N JAOA
• Status: Completed
• Phase: N/A
• First received: September 29, 2009
• Last updated: September 30, 2009
• Start date: April 2009
• Est. completion date: September 2009

Study information

• Verified date: September 2009
• Source: EMG Labs of Arizona Arthritis & Rheumatology Associates
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

Carpal tunnel syndrome is caused by compression of the median nerve at the wrist. The hypothesis is that ultrasound imaging can be used to visualize nerve compression in carpal tunnel patients during hand activity, and normal subjects will not demonstrate any nerve compression.

Description:

Two patients with carpal tunnel syndrome underwent nerve testing to document that they had median nerve abnormality at the wrist. They subsequently had ultrasound imaging of the wrist at rest and during a stress test using hand activity. Two control subjects had nerve testing to prove that they had no nerve abnormality at the carpal tunnel. The carpal tunnel syndrome patients demonstrated nerve compression on the ultrasound images during the stress tests and the normal subjects showed no nerve compression.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 4
• Est. completion date: September 2009
• Est. primary completion date: September 2009
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years to 90 Years

Eligibility

Inclusion Criteria:

• Patients must have symptoms consistent with carpal tunnel syndrome and electrodiagnostic testing that demonstrates abnormal median nerve function at the wrist, consistent with carpal tunnel syndrome.

• Normal subjects must have no upper limb symptoms to support carpal tunnel syndrome and normal nerve testing.

Exclusion Criteria:

• Patients excluded if nerve testing was not consistent with carpal tunnel syndrome.

• Normals excluded if nerve testing demonstrated any median nerve abnormality.

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

• Carpal Tunnel Syndrome
• Syndrome

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
EMG Labs of Arizona Arthritis & Rheumatology Associates

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Median nerve compressive narrowing on ultrasound imaging in carpal tunnel syndrome patients		5 months	No
Secondary	No median nerve compressive narrowing in normal subjects		5 months	No