Sonographic Follow-up of Patients With Carpal Tunnel Syndrome Undergoing Surgical or Conservative Treatment

Carpal Tunnel Syndrome Clinical Trial

— CTS  

Official title:

Sonographic Follow-up of Patients With Carpal Tunnel Syndrome Undergoing Surgical or Conservative Treatment: Prospective Cohort Study.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00694265
• Other study ID #: CTU_CTS
• Secondary ID: UBern_CTS
• Status: Completed
• Phase: N/A
• First received: June 6, 2008
• Last updated: August 25, 2008
• Start date: January 2002
• Est. completion date: December 2003

Study information

• Verified date: August 2008
• Source: University of Bern
• Contact: n/a
• Is FDA regulated: No
• Health authority: Switzerland: Ethikkommission
• Study type: Observational

Clinical Trial Summary

In wrists with carpal tunnel syndrome (CTS) the sonographically measured largest cross-sectional area (CSA) of the median nerve is increased. We compared the changes in largest CSA in wrists undergoing surgical decompression and wrists undergoing conservative treatment of CTS.

Description:

Objective:

In wrists with carpal tunnel syndrome (CTS) the sonographically measured largest cross-sectional area (CSA) of the median nerve is increased. We compared the changes in largest CSA in wrists undergoing surgical decompression and wrists undergoing conservative treatment of CTS.

Methods:

Prospective cohort study in 55 consecutive patients with 78 wrists with established CTS, including 60 wrists with surgical decompression and 18 wrists with conservative treatment. A sonographic examination was scheduled before and at 4 months after initiation of treatment. Changes in CSA between wrists with surgical and wrists with conservative treatment were compared using linear regression models.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 55
• Est. completion date: December 2003
• Est. primary completion date: June 2003
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• wrists with established CTS

Exclusion Criteria:

• prior surgery for CTS

• traumatic lesions

• coexistent neurological disease

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Carpal Tunnel Syndrome
• Syndrome

Intervention

Procedure:
• Decompression
Surgical decompression of the median nerve
• Conservative treatment
Conservative treatment typically consisted of splinting and corticosteroid injections

Locations

Country	Name	City	State
Switzerland	Dep. of Plastic and Hand Surgery, Bern University Hospital	Bern

Sponsors (1)

Lead Sponsor	Collaborator
University of Bern

Country where clinical trial is conducted

Switzerland, 

References & Publications (2)

Bachmann LM, Jüni P, Reichenbach S, Ziswiler HR, Kessels AG, Vögelin E. Consequences of different diagnostic "gold standards" in test accuracy research: Carpal Tunnel Syndrome as an example. Int J Epidemiol. 2005 Aug;34(4):953-5. Epub 2005 May 23. — View Citation

Ziswiler HR, Reichenbach S, Vögelin E, Bachmann LM, Villiger PM, Jüni P. Diagnostic value of sonography in patients with suspected carpal tunnel syndrome: a prospective study. Arthritis Rheum. 2005 Jan;52(1):304-11. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Measure of the largest cross-sectional area (CSA) of the median nerve		Before and 4 months after initiation of treatment	No