Cardiac Output and Duplex Sonography in Carotid Endarterectomy

Carotid Stenosis Clinical Trial

Official title: Cardiac Output and Cerebral Blood-flow During Carotid Endarterectomy in Regional vs. General Anesthesia. A Prospective Randomized Controlled Single Center Study

Status Completed

Clinical Trial Summary

The aim of this study is to investigate the differences between the cardiac output and the cerebral blood-flow between a regional anesthesia (RA) and a general anesthesia (GA) in a randomized, controlled, single center study at the Medical University Innsbruck, Department of Anesthesia and Intensive Care Medicine.

Clinical Trial Description

The investigators will investigate the differences between the cardiac output and the cerebral blood-flow between a regional anesthesia (RA) and a general anesthesia (GA) in a randomized, controlled, single center study at the Medical University Innsbruck, Department of Anesthesia and Intensive Care Medicine.

For this purpose patients with the need of a carotid endarterectomy (CEA) will be included and randomized either to the regional anesthesia (RA) or the general anesthesia (GA) group until a patient number of 45 in each group is achieved.

The cardiac output and cerebral blood-flow via trans-cranial Doppler (TCD) will be measured at 6 time points:

• T0 Baseline (after insertion of an arterial line)

• T1 After induction of anesthesia, but before surgical start

• T2 Two minutes after clamping the carotid artery

• T3 Two minutes after shunt insertation of the carotid artery

• T4 After reperfusion

• T5 After completion of the skin suture ;

Related Conditions & MeSH terms

• Carotid Stenosis

• NCT number: NCT02230358
• Study type: Interventional
• Source: Medical University Innsbruck
• Status: Completed
• Phase: N/A
• Start date: July 2014
• Completion date: July 2017