Impact of Aspiration Thrombectomy During Carotid Stenting

Status Recruiting

Clinical Trial Summary

The purpose of this study is to determine whether aspiration thrombectomy following carotid stent deployment will reduce the number of procedure related signals as identified by diffusion weighted MRI of the brain.

Clinical Trial Description

Studies have demonstrated that carotid artery stenting is a safe and effective alternative to carotid endarterectomy for high or standard risk patients with symptomatic stenosis. Despite the routine use of embolic protection devices, numerous studies have shown that carotid stenting is associated with a higher degree of intracranial emboli by diffusion-weighted MRI of the brain. A potential solution to minimize this effect is the use of aspiration prior to distal embolic protection removal. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01550835
Study type	Interventional
Source	Fogarty Clinical Research Inc.
Contact	Betty deBettencourt, RN
Phone	650-962-4566
Email	betty.debettencourt@fogartyinstitute.org
Status	Recruiting
Phase	N/A
Start date	February 2012

View Details

See also
Status	Clinical Trial	Phase
Active, not recruiting	`NCT03931161` - Effect of Evolocumab on Carotid Plaque Composition in Asymptomatic Carotid Artery Stenosis (EVOCAR-1)	Phase 4
Recruiting	`NCT03353103` - Imaging of Unstable Carotid Plaque in Patient Referred to Endarterectomy	Phase 2
Completed	`NCT03996148` - Time to Post-Anesthesia Neurological Evaluation With Three Different Anesthetic Techniques	Phase 4
Recruiting	`NCT05968053` - Detection of Microplastics and Nanoplastics in Neurosurgery Patients (DT-MiNi)
Completed	`NCT00597974` - Neurological Outcome With Carotid Artery Stenting	N/A
Completed	`NCT00318851` - Carotid Artery Stenting With Protection Registry	Phase 3
Active, not recruiting	`NCT05293067` - Troponin In Carotid Revascularization
Completed	`NCT03133429` - Clinical Study to Evaluate the Safety and Effectiveness of MER® Stents in Carotid Revascularisation.	N/A
Recruiting	`NCT01440036` - The Correlation Between the Enzyme Paraoxigenase 1 (PON1) to Carotid Artery Atheromatous Plaque	N/A
Completed	`NCT00417963` - ViVEXX Carotid Revascularization Trial (VIVA)	Phase 3
Completed	`NCT00177346` - A Randomized Trial of Carotid Artery Stenting With and Without Cerebral Protection	N/A
Recruiting	`NCT05574972` - Timing Carotid Stent Clinical Study for the Treatment of Carotid Artery Stenosis（Timing Trial）	N/A
Recruiting	`NCT02476396` - Structural Stability of Carotid Plaque and Symptomatology
Completed	`NCT05451485` - VFI in Healthy Vessels
Recruiting	`NCT06033963` - Safety and Efficacy of Remote Ischemic Conditioning in Patients With Carotid Artery Stenosis Receiving Carotid EndArterectomy	N/A
Not yet recruiting	`NCT02224209` - Comparison of Staged Angioplasty and Routine Single-stage Stenting (CAS) in the Treatment of Carotid Artery Stenosis	Phase 4
Completed	`NCT02006095` - Neuroimaging Correlates of Memory Decline Following Carotid Interventions
Terminated	`NCT01236508` - Relation of Carotid Artery Plaque Inflammation, Covert Stroke and White Matter Disease	Phase 4
Recruiting	`NCT05126238` - A Lithium-Based Medication to Improve Neurological Outcomes After Surgical Carotid Reconstruction	Phase 3
Recruiting	`NCT06170580` - Improved Image Quality for Assessment of Carotid Artery Stenosis by Ultrafast Ultrasound FLOW Imaging