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Caries, Dental clinical trials

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NCT ID: NCT06365281 Not yet recruiting - Dental Caries Clinical Trials

Caries Prevalence, Experience and Risk Related Factors Among Early Middle-aged Patients Attending Cairo University

Start date: May 2024
Phase:
Study type: Observational [Patient Registry]

Dental caries, a widespread oral health issue, results from a complex interplay of factors including behavior, hygiene, diet, and socio-demographic aspects. While preventive measures are available, it remains prevalent globally, affecting numerous teeth per individual. Improved oral hygiene practices and increased awareness have led to a reduction in caries prevalence. However, rising sugar consumption exceeds dietary guidelines, contributing to the problem. Despite limited epidemiological studies in Egypt, addressing individual-level factors is crucial. Surveillance of oral health in the early middle age group is standard, allowing decision-makers to assess the impact of caries and oral health care provision. Stratifying data by age, geography, and gender aids in understanding prevalence and planning effective prevention strategies. Overall, promoting awareness of dietary habits and preventive practices is vital for improving oral health outcome So, The purpose of this study is to assess the prevalence of dental caries among early middle age patients attending dental hospital in Faculty of Dentistry, Cairo university and to analyze the related risk factors utilizing WHO Oral Health Questionnaire for Adults.

NCT ID: NCT06317857 Not yet recruiting - Caries, Dental Clinical Trials

Clinical Performance of an Alkasite-based Restorative Material

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

The evolution of restorative dental materials and technology has enabled the use of tooth-colored restorative materials in dental restorations, with all dentists hoping for the presence of materials that combine biocompatible qualities and aesthetics . Although resin composite materials' mechanical and aesthetic properties have greatly improved over the past 20 years, research is currently on to find ways to prevent secondary caries from forming beneath and at the margins of restorations. In order to circumvent these problems, there is a growing tendency towards the use of resin-based bioactive and remineralizing restorative materials to strengthen and lengthen the lifespan of bonded dental restorations.

NCT ID: NCT06063239 Not yet recruiting - Clinical trials for Intellectual Disability

Probiotics in Special Needs Patients at High Risk for Tooth Decay: a Randomized Controlled Trial.

Start date: October 1, 2023
Phase: N/A
Study type: Interventional

The goal of this randomized clinical trial is to test the effect orally administration of Probiotics based on Lactobacillus rhamnosus LR04 and Lactobacillus plantarum LP14 as adjuvant in caries prevention in subjects who can not properly perform oral hygiene procedures. The main questions it aims to answer are: - QUESTION 1: orally administered probiotics based on the previous strains could represent a useful tool in support of special needs patients in tooth decay prevention? - QUESTION 2: orally administered probiotics based on the previous strains could ameliorate salivary pH management? Partecipants in the test group will take the test probiotic for 90 days in adjunction of the routinary oral hygiene procedures. Partecipants in the positive controlled group will take the placebo for 90 days in adjunction of the routinary oral hygiene procedures. Partecipants in the negative control group will perform only the routinary oral hygiene procedures. Researchers will compare 3 groups to see if orally administered probiotics based on L. rhamnosus and L. plantarum may help in the management of clinical status and salivary pH levels.

NCT ID: NCT05943782 Not yet recruiting - Caries,Dental Clinical Trials

Evaluation of CAD/CAM Onlays Fabricated by Subtractive Versus Additive Digital Manufacturing Techniques.

Start date: March 1, 2024
Phase: N/A
Study type: Interventional

Aim of the study: The aim of this RCT is to evaluate CAD/CAM onlays fabricated by subtractive technique (brilliant crios) versus additive technique (varseosmile crown plus material), in terms of clinical functional evaluation following the FDI criteria and three-dimensional digital evaluation of the marginal and internal fit by triple scan protocol. Materials and methods: A total of 30 patients will be enrolled in the clinical trial following the eligibility criteria. Then, the patients will be randomly allocated to receive either 3D printed onlays or milled ones. A blinded operator will prepare a standardized cavity for the restoration and an impression will be performed. After designing the restoration on the Exocad software, A dentist not involved in the clinical part of the study will receive the STL file of the design and envelopes containing the information necessary only to manufacture the restorations (tooth numbers and restorative materials) to proceed with either the milling or printing procedures. Try in and cementation procedures will be similarly performed for both groups by a blinded operator. Finally, the marginal and internal fit will be evaluated by using the triple scan protocol for digital 3D assessment. Also, a baseline, six months and 12 months assessments will be performed by a blinded examiner, not involved in the clinical part for assessing the functional clinical performance of the re3stprations using the FDI criteria. Finally, the data will be statistically analyzed.

NCT ID: NCT05792800 Not yet recruiting - Caries,Dental Clinical Trials

Dental Practitioners KAP Regarding Caries Preventive Measures in Cairo and Riyadah

Start date: September 2023
Phase:
Study type: Observational

The study aims to evaluate the knowledge, attitude, and practice of dental practitioners from Cairo and Riyadh regarding caries preventive measures.

NCT ID: NCT05792215 Not yet recruiting - Caries,Dental Clinical Trials

KAP of Dental Practitioners Regarding CRA

Start date: September 2023
Phase:
Study type: Observational

The aim of the study is to evaluate the knowledge, attitude, and practice of a group of dental practitioners from Cairo and Riyadh regarding caries risk assessment and management.

NCT ID: NCT05306691 Not yet recruiting - White Spot Lesion Clinical Trials

Remineralizing Efficacy of Giomer Varnish vs. Fluoride Varnish in Management of White Spot Lesions in Adult Patients

Start date: May 15, 2022
Phase: Early Phase 1
Study type: Interventional

To evaluate the remineralizing capability of biosmart S-PRG barrier coat varnish and its employment in clinical practice

NCT ID: NCT05276154 Not yet recruiting - Caries,Dental Clinical Trials

Clinical Performance of Thermoviscous Bulk Fill Resin Composites in Comparison to Conventional Packable Bulk Fills

Start date: April 15, 2022
Phase: N/A
Study type: Interventional

This clinical trial will be conducted to compare the clinical performance of the thermo-viscous preheated bulk fill composite in the management of carious lesions in posterior teeth in adult patients over 12 months.

NCT ID: NCT04945382 Not yet recruiting - Caries,Dental Clinical Trials

Retention of a Flowable Resin-based Sealant With Two Types of Adhesives

Start date: June 2021
Phase: N/A
Study type: Interventional

The aim of the present study is to compare the use of two adhesives for the placement of occlusal sealants, evaluating their retention on the occlusal surfaces. Methods: A randomized clinical trial, in Phase IV, triple-blind, with a split mouth study design will be adopted, which consists of a simple division of the mouth into two parts (right and left) for the first four permanent molars of each patient, where the placement of the materials will be on the right / left side of the mouth and contralateral. They will then be randomly assigned following block randomization procedures with a 1: 1 allocation. 50 participants (6-year-old children) will be considered, and a pair of permanent first molars homologs will be used for each participant. Inclusion criteria include: children whose parents accepted their participation in the study and who signed the Informed Consent, children enrolled in the Pichanaki District school, children who present upper and / or lower permanent molars with absence of deep caries cavities and caries, graded 0 and 1 according to ICDAS II, Green and Vermillion Simplified Oral Hygiene Index of 1-2, have a pair of non-cavitated caries-free counterparts, and children with positive behavior. After selection of patients, the dental sealants will be placed with two different adhesives: the 8th generation adhesive intervention group (Scotchbond universal 3M) and the 5th generation adhesive control group (Single bond 3M), both sealants will use the same flowable resin (Tetric N-flow ivoclar vivadent). Results evaluation: Retention of the sealants will be evaluated at 6, 9 and 12 months. Retention rates of pit and fissure sealant materials will be analyzed according to the split mouth design. The study will use the Mc Nemar test to compare the retention of sealants in the intervention group and the control group at 6, 9 and 12 months. A 95% confidence level will be accepted. In addition, the Cochrane Q test will be applied to determine if there are significant differences in survival for each group of sealants through the evaluation time. The calculation of the survival months of the sealants will be carried out using the actuarial method (survival tables). Expected conclusion: To identify which of the two adhesives presents the best retention after 12 months.

NCT ID: NCT04422860 Not yet recruiting - Caries,Dental Clinical Trials

Remineralization Efficacy of Gum Arabic Varnish.

Start date: October 2020
Phase: Phase 2/Phase 3
Study type: Interventional

The aim of this study is to evaluate the remineralizing capacity of Gum Arabic varnish and its implementation into clinical practice.