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Postprandial Monocyte Maturation and Vascular Dysfunction Following High-Fat Meals - Study 1

Cardiovascular Risk Factor Clinical Trial

Official title:
Postprandial Monocyte Maturation and Vascular Dysfunction Following High-Fat Meals: The Impact of Cardiovascular Fitness and Acute Aerobic Exercise - Study 1

Clinical Trial Summary

The purpose of this research study is to examine the effect of high-fat meals on the health of blood vessels. In addition, the study will examine how exercise/fitness/physical activity impacts blood vessels after consumption of a high-fat meal.

Clinical Trial Description

This is the first in a series of studies examining the impact of high-fat meals on blood vessels. During the preliminary visit of this study, eligible participants' resting metabolic rate, arm flow mediated dilation, and leg flow mediate dilation will be measured. They will complete handgrip and plantar flexion exercise tasks. Finally, they will be given a physical activity monitor to wear for 7 days. At their first visit, participants will eat a high-fat meal and blood will be drawn to measure blood vessel health. They will also repeat the arm flow mediated dilation, leg flow mediate dilation, handgrip, and plantar flexion exercise tests. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03958734
Study type Interventional
Source Virginia Commonwealth University
Contact
Status Completed
Phase N/A
Start date June 17, 2019
Completion date April 29, 2021
View Details
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