Cardiovascular Diseases Clinical Trial
Official title:
Imaging of Retinochoroidal Vasculature in Patients Being Assessed for Cardiovascular Disease
This study aims to determine whether changes in retinal vasculature seen on SS-OCTA can be correlated to degree of cardiovascular disease as measured by carotid duplex ultrasonography.
Status | Recruiting |
Enrollment | 50 |
Est. completion date | December 31, 2024 |
Est. primary completion date | December 31, 2024 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 80 Years |
Eligibility | Inclusion Criteria: - Subjects between 18 and 80 years of age. - No known prior history of retinal disease. - Able to participate in a clinical eye examination setting. - Able to consent. - Subjects receiving standard of care carotid duplex ultrasounds. Exclusion Criteria: - Known ophthalmologic disease (e.g. glaucoma, macular degeneration, ocular injury) other than corrected refractive error. - Lack of capacity to provide informed consent. - Subjects younger than 18 years of age or older than 80 years of age. - History of stroke or acute loss of vision. - Unable to participate in a clinical eye examination setting. |
Country | Name | City | State |
---|---|---|---|
United States | Northwestern University/Northwestern Medical Group, Department of Ophthalmology | Chicago | Illinois |
Lead Sponsor | Collaborator |
---|---|
Northwestern University |
United States,
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* Note: There are 20 references in all — Click here to view all references
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Correlation with and prediction of the presence/degree of carotid occlusive disease as determined by carotid duplex ultrasonography | Determining whether measures taken from SS-OCTA, color fundus photography, and retinal exams can correlate with and predict the presence/degree of carotid occlusive disease as determined by carotid duplex ultrasonography by examining the following parameters: retinal vessel caliber, retinal vessel density, retinal vessel perfusion, retinal vessel tortuosity, presence of Hellenhorst or other plaques, and/or areas of ischemia. | 2 hours |
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