A Cohort Study of Chronic Cardiovascular Diseases

Cardiovascular Diseases Clinical Trial

Official title:

A Cohort Study of Chronic Cardiovascular Diseases in the Department of Cardiology, Peking University First Hospital

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04996342
• Other study ID #: CVDcohort
• Status: Recruiting
• Start date: April 15, 2021
• Est. completion date: December 2025

Study information

• Verified date: August 2021
• Source: Peking University First Hospital
• Contact: Jia Jia
• Phone: 861083572283
• Email: jiajia9985[@]163.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This prospective cohort study aims to establish cohorts of patients with chronic cardiovascular disease, including refractory and secondary hypertension, coronary heart disease, atrial fibrillation, ventricular arrhythmias, structural heart disease, pulmonary hypertension, heart failure and rare diseases of the cardiovascular system, and patients with implantations of cardiac pacemaker, in order to dynamically describe the population characteristics, diagnosis and treatment status and long-term prognosis and analyze the factors affecting the choice of treatment plan, long-term management quality and clinical prognosis of these patients.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 10000
• Est. completion date: December 2025
• Est. primary completion date: December 2025
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

This study includes 9 disease-specific cohorts. The specific inclusion and exclusion criteria are as following:

1. Refractory and secondary hypertension

Inclusion Criteria:

• Patients diagnosed as refractory hypertension and/or secondary hypertension

• Patients willing to accept long-term follow-up and regular return visits

Exclusion Criteria:

• Severe diseases of other systems may affecting the life span of patients

2. Coronary heart disease

Inclusion Criteria:

• Patients undergoing coronary angiography and interventional therapy in the cath lab

• Patients undergoing coronary angiography and functional assessment in the cath lab

• Patients diagnosed as acute myocardial infarction

Exclusion Criteria:

• Severe diseases of other systems may affecting the life span of patients

• Regular return visits not available

3. Atrial fibrillation

Inclusion Criteria:

• PAtrial fibrillation diagnosed by electrocardiogram or holter (duration >30 seconds)

• Patients willing to accept long-term follow-up and regular return visits

Exclusion Criteria:

• Severe diseases of other systems may affecting the life span of patients

• New-onset atrial fibrillation during the perioperative period of major surgery

4. Ventricular arrhythmias

Inclusion Criteria:

• Patients diagnosed as ventricular tachycardia, ventricular premature beat

• Patients willing to accept long-term follow-up and regular return visits

Exclusion Criteria:

• Severe diseases of other systems may affecting the life span of patients

• A transient cause of ventricular arrhythmia was determined by the doctor, and long-term follow-up was not required

5. Cardiac pacemaker implantation

Inclusion Criteria:

• Patients with permanent pacemaker implantations due to various causes (including bradycardia pacing, implantable cardioverter defibrillator, cardiac resynchronization therapy, leadless cardiac pacemaker, etc.)

• Patients willing to accept long-term follow-up and regular return visits

Exclusion Criteria:

• Severe diseases of other systems may affecting the life span of patients

6. Structural heart disease

Inclusion Criteria:

• Patients diagnosed as structural heart disease, including congenital heart disease and severe valvular disease (moderate and above valvular stenosis or incomplete closure)

• Patients willing to accept long-term follow-up and regular return visits

Exclusion Criteria:

• Severe diseases of other systems may affecting the life span of patients

7. Pulmonary hypertension

Inclusion Criteria:

• Patients diagnosed as pulmonary hypertension

• Patients willing to accept long-term follow-up and regular return visits

Exclusion Criteria:

• Severe diseases of other systems may affecting the life span of patients

8. Heart failure

Inclusion Criteria:

• Patients diagnosed as heart failure

• Patients willing to accept long-term follow-up and regular return visits

Exclusion Criteria:

• Severe diseases of other systems may affecting the life span of patients

9. Rare diseases of the cardiovascular system

Inclusion Criteria:

• Patients diagnosed as rare diseases in the catalog published by National Health Commission of the People's Republic of China

• Patients willing to accept long-term follow-up and regular return visits

Exclusion Criteria:

• Severe diseases of other systems may affecting the life span of patients

Related Conditions & MeSH terms

• Cardiovascular Diseases
• Cohort Studies

Locations

Country	Name	City	State
China	Division of Cardiology, Peking University First Hospital	Beijing	??

Sponsors (1)

Lead Sponsor	Collaborator
Peking University First Hospital

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Major Adverse Cardiovascular Events	Time to the first occurence of Any cause death, myocardial infarction, or Stroke	5 year