Physical Capacity in Hodgkin Lymphoma Survivors

Status Recruiting

Clinical Trial Summary

The study aims to investigate if physical capacity obtained in the cardiopulmonary exercise test can predict cardiovascular alterations in Hodgkin Lymphoma (HL) Survivors. In addition, to study the effects of exercise training on physical capacity and cardiovascular responses in these patients.

Clinical Trial Description

Hodgkin Lymphoma (HL) is a hematological neoplasia that mainly affects young people. Anthracycline-based chemotherapy, followed or not by mediastinal radiotherapy, substantially improves prognosis in this set of patients. Observational studies have shown that cardiovascular disease is the most non oncologic cause of death in this population. Coronary artery disease (CAD) affects 26% of survivors after 10 years of absence of HL . However, the early intervention and the assessment to predict the cardiovascular risk remain little known. In this study, the investigators will test the hypothesis that physical capacity can predict the cardiovascular alterations in HL Survivors. In addition, exercise training improves physical capacity and heart rate responses in this set of patients. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04636255
Study type	Interventional
Source	University of Sao Paulo General Hospital
Contact	Luciana S Santos
Phone	551126615043
Email	gglusantos@gmail.com
Status	Recruiting
Phase	N/A
Start date	October 21, 2017
Completion date	October 21, 2023

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